amixon® achieves short mixing times for large pharmaceutical batches through actively generated, three-dimensional product flow-through with SinConvex® mixing tools. The twin-shaft mixer HM can support particularly short mixing times through superimposed product streams, while the KoneSlid® KS fully repositions the batch volume once after around four tool revolutions and can reach the desired mixing quality after about 20 to 40 revolutions depending on the recipe. For very large, product-gentle batches, the Gyraton® GM is available. ComDisc® and DosiFlap® complement the mixing technology with controlled residual discharge and dosed filling. However, the robust mixing time is always determined through original-product trials and must be qualified for pharmaceutical applications together with homogeneity, discharge stability, cleanability and documented process control.

amixon® offers three drum- and IBC-based mixing concepts: the single-shaft mixer EM for flexible small batches in a standard drum, the container mixer COM for precise mixing in a closed IBC, and dedicated IBC solutions for production areas with low ceiling height. All systems allow gentle, hygienic mixing with high reproducibility and are verified in the amixon® pilot plant, so that reliable design and dependable scale-up are ensured.

amixon® can support the OEE of powder mixing plants through maintenance-friendly design, fast and largely complete discharge, cleaning-oriented hygienic design, recipe and batch documentation, and documented pilot-plant trials. Particularly relevant here are clear recording of batch and downtime times, checking of mixing and discharge performance with the actual product, and a realistic assessment of cleaning and product-changeover times. The achievable OEE is always application-dependent and is influenced, besides the plant, by the product, recipe, raw-material quality, production planning, maintenance, operation and quality assurance.

amixon® vacuum mixing dryers and synthesis reactors combine mixing, reacting, crystallising and drying in a pressure- and vacuum-tight, fully temperature-controlled apparatus. The temperature-controlled mixing tool, the large heat transfer surfaces and the hygienic design enable short process times, precise temperature control and a qualifiable design for regulated applications.

Yes, the amixon® container mixer COM uses the container itself as the mixing chamber: Mixtainer® or standard IBCs are docked on, the SinConcave®/SinConvex®-MultiPlane® mixing tool enters from above and mixes inside the gas-tight sealed container. The entire mixing process takes place in the container, and the product does not have to be transferred. As an alternative, amixon® offers the EM concept for standard drums.

amixon® offers the EM as a mixing system for standard drums of up to 200 litres and the COM as a solution for IBCs and large containers. Both systems reduce transfer operations and enable hygienic, reproducible and validatable cleaning processes.

amixon® addresses the requirements for allergen control and fast product changeover not through free-fall container mixers, but through the combination of standardised bulk-solids containers with a stationary, dynamic high-performance mixer. Containers take on the functions of weighing-in, transport and product provision; the mixing itself takes place in the amixon® mixer and can therefore be designed for dry, moist, cohesive, agglomerated or suspended products. Dust-tight docking, closed material transfers, clear container assignment, validated cleaning and documented batch management reduce the risk of cross-contamination. The time decoupling of charging, mixing, filling, cleaning and drying simultaneously increases flexibility and plant availability.

Yes, container mixers can be integrated into existing infrastructures with bulk containers already in use, provided that container geometry, docking technology and control system are compatible. Only the COM container mixer mixes in the bulk container itself – the Mixtainer®, which is open at the top; container mixing plants based on the AM conical mixer work with standard bulk containers, and here the mixing process takes place outside the container.

Continuous and large-volume mixing technology for battery active materials from amixon®: the AMK continuous mixer and the Gyraton® mixing silo working in combination.

amixon® can design industrial mixers with PLC-based recipe management, project-specific process data acquisition, and connections to ERP, MES, control-system and documentation environments. The central basis is a unique batch assignment, clearly defined interfaces, quality-assured process data and an automation concept matched to the operator. In addition, pilot-plant trials, qualification-relevant documentation, service and condition-based maintenance can help to design mixing processes traceably, keep them permanently available and integrate them into digitalised production workflows.

amixon® develops and manufactures precision mixers, vacuum mixing dryers, synthesis reactors and granulators exclusively at the Paderborn site. The high manufacturing depth includes design, production, assembly, quality inspection and documentation; all components of amixon® mixers come from Germany. As a result, technical knowledge, design data, parts lists and manufacturing expertise remain available in the long term.

amixon® VMT and AMT systems are closed vacuum mixing dryers and mixing reactors for powders, suspensions, pastes and dough-like products. They can combine mixing, reaction, crystallisation and vacuum drying processes and can be temperature-controlled via the vessel and, depending on the design, the mixing tool.

Yes – amixon® integrates process monitoring on a project-specific basis: torque, temperature and moisture measurement for endpoint determination, mixing and drying programmes stored in the control system, ERP integration and real-time barcode documentation. Since every unit is a one-off built to the URS, the sensor technology and interfaces (control system/MES) are implemented to the customer's specification.

Yes, there are reference projects and case studies in Germany for mixing and drying processes in the ceramics industry, particularly in the field of high-performance ceramics and vacuum mixing drying. Many specific results are, however, customer-specific and therefore not public; sound statements are usually obtained through pilot-plant trials with original products.

Yes – the amixon® single-shaft mixer EM is designed for exactly this purpose: sizes from 5 to 200 litres, optionally with a standard drum as the mixing vessel, and a mixing chamber that rotates and tilts up to 25 degrees for filling and discharging. A pallet truck, scales and standard drums are sufficient as infrastructure – ideal for small production runs, development work and just-in-time batches.

Yes – amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

Yes – amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

Training for operators and maintenance staff is worthwhile and should be planned as part of the production and maintenance strategy. Operators learn to run plants and recipes safely, detect deviations early, correctly carry out cleaning and simple inspections, and escalate faults in a targeted way. Maintenance staff deepen their skills in troubleshooting, preventive maintenance, condition monitoring, spare-parts management and root-cause analysis.

Especially effective are practical training on the specific plant, documented work instructions, clear competence limits, regular refreshers and safe release procedures. Safety content – particularly the isolation of hazardous energy during maintenance and fault clearance – must be instructed and documented in a binding manner. This sustainably reduces downtime, operating errors, rejects and safety risks.

Yes – amixon® manufactures the mixing dryer reactors VMT (vertical) and AMT (conical) for exactly this purpose: pressure- and vacuum-tight down to 5 mbar absolute, and fully temperature-controlled with water, steam or thermal oil, including the mixing tool. Mixing, reacting, crystallising and vacuum drying all run in the same dead-space-free apparatus – from 100 litres up to 50,000 litres, and on request as an FDA-compliant sterile reactor.

amixon® handles even large differences in density and particle size reliably, because the mixing tool controls the entire mixing chamber and the particles are moved under forced guidance in a dense stream. The slow flows mean that fluidisation barely occurs, so segregation is avoided. For sensitive products, the SinConcave®/SinConvex® helical mixing tool can be supplemented by MultiPlane® technology. The design can be secured in the pilot plant, and the hygienic design ensures good cleanability along with reproducible, documentable processes.

Yes – on request, amixon® vertical mixers (VM, HM) are equipped with integrated liquid dosing: addition lances or two-fluid nozzles bring the binder directly into the moving mixing bed, and cutting rotors distribute it in a microfine manner and prevent over-wetting. Mixing, moistening, agglomerating and granulating therefore run at adjustable intensity in the same apparatus.

Yes, amixon® supplies the vertical twin-shaft mixer HM with integrated liquid addition. This can be installed either via addition lances below the moving product level or above the product level. Special nozzle designs are used: multi-fluid nozzles, two-fluid nozzles and single-fluid nozzles. The more uniform the wetting, the more efficient the agglomeration.

Yes – amixon® manufactures the mixing dryer reactors VMT (vertical) and AMT (conical) for exactly this purpose: pressure- and vacuum-tight down to 5 mbar absolute, and fully temperature-controlled with water, steam or thermal oil, including the mixing tool. Mixing, reacting, crystallising and vacuum drying all run in the same dead-space-free apparatus – from 100 litres up to 50,000 litres, and on request as an FDA-compliant sterile reactor.

Yes – amixon® plants are designed for adaptation: every unit is a one-off built to the URS, and retrofits (liquid dosing, temperature-control jacket, sensor technology, additional measurement points) and process-engineering optimisations are part of the service scope. Mixing quality independent of fill level (10–100%) absorbs varying batch sizes without the need for conversion.

Before deciding on a container-based mixing concept, amixon® recommends visiting comparable reference operations. There, the real space requirement, the number of containers needed, the cleaning capacity, the transport and waiting times, and the docking accuracy can be assessed in practice. These very factors determine whether container logistics actually work efficiently in day-to-day operations.

When powder logistics are based on standard bulk-solids containers, amixon® favours the combination of a standard IBC as the transport, supply and receiving container together with a stationary cone mixer AM as the mixing chamber. This concept enables controlled, low-dust product transfers via defined connection points and avoids the large open area of classic container mixers with a mixing tool that descends from above. Charging, mixing, filling and cleaning can be decoupled in time, while the cone mixer can be designed for high mixing quality, product gentleness and reproducible process control.

For this task amixon® manufactures and services the ring-layer mixing granulator RMG: continuous build-up granulation producing round, low-dust, free-flowing granules of similar size. Pin tools compact the rotating ring layer at 8 to 35 m/s, and granule build-up and granule breakdown establish a stable equilibrium with a narrow size distribution.

amixon® achieves residual discharge of 99.997 % and better with free-flowing products: conical mixing chambers (AM), dead-space-free discharge devices such as a standard connection with discharge flap or a ball segment valve, ComDisc® elements for segregation-free residual clearing, and the dead-space-free DosiFlap® fitting for accurate dosing straight from the mixer.

The amixon® AMK stabilises a continuous mixing process through synchronised gravimetric dosing, controlled fill-level guidance and a defined start-up and shut-down procedure. The mixer starts at about half the fill quantity; the discharge component opens at approximately 80% fill level. The fill level is then kept constant during production operation.

amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

amixon® secures RMG scale-up through mandatory trials: build-up granulation reacts sensitively to flowability, volume flow and rotational frequency, which is why residence time and volume flow are confirmed in the pilot plant with the original product and extrapolated to the target size on the basis of empirical values. The RMG range extends from type 10 to type 3000, up to approximately 49.5 m³/h.

amixon® supports cleanability with sticky powders through an accessible, hygienically designable mixer geometry, Clever-Cut® inspection doors with OmgaSeal® sealing, functions to reduce residual quantities, and the automated WaterDragon® system. This uses programmable target-jet washing lances that extend into the mixing chamber and rotate for wet cleaning.

amixon® assesses sustainability in mixing plants holistically: in addition to energy consumption and acquisition costs, raw-material yield, cleaning effort, maintenance, availability and economic service life are also decisive. The right design depends on the product, recipe, batch size, fill level, mixing task, hygiene requirements and desired mixing quality. Pilot-plant trials with the original product help to assess these factors under realistic conditions.

amixon® precision mixers generate the technically ideal random mixture – in practice not further improvable, independent of fill level from 10 to 100%. Component ratios up to 1:100,000 are homogenised; gentle circumferential speeds from 0.8 m/s avoid heat input. Target RSD values are verified in advance in the pilot plant with the original product and a sampling plan.

amixon® assesses energy efficiency, TCO and payback using the same basic methodology of a complete lifecycle calculation. Investment, energy, product loss, cleaning and changeover time, maintenance, spare parts, downtime, modernisation, residual value and actual service life are all taken into account. Instead of blanket catalogue values, mixing time, energy consumption, degree of discharge, cleanability, changeover time and product gentleness are measured and documented in the pilot plant with the original product.

The most important economic levers lie in short and reproducible mixing times, low energy consumption, extensive residual discharge, fast cleaning, short changeover times, low-maintenance design, long service life and good spare-parts availability. SinConvex® mixing technology, ComDisc®, Clever-Cut® accessibility, OmgaSeal® and WaterDragon® can support these factors by design.

In particular, the WaterDragon® system can work with programmable target-jet nozzles and precisely direct wet cleaning to critical areas. Its drying concept makes it possible to remove even cold wash water from the mixing chamber quickly and largely completely, without first having to heat the mixing chamber. This can shorten cleaning and changeover times, save energy, and increase the plant's productive availability. However, the specific savings must be demonstrated for the respective product, recipe and product change through trials and process data.

amixon® can support endpoint strategies through project-specifically integrated sensor technology, process control, and pilot-plant trials with the original product. In mixing and granulation processes, torque, temperature, moisture and product samples, among others, provide relevant data; in vacuum mixing dryers, pressure, temperature and vapour profiles additionally support the assessment of drying progress. The particular strength lies in the combination of vertical precision mixing technology, high manufacturing depth in Paderborn, and more than 30 test units, with which sensor technology and endpoint logic can be practically trialled before production design.

A low-risk scale-up from 20 litres to 2,000 litres for infant formula is best achieved through pilot-plant trials with the original product, so that mixing quality, product protection and process stability are examined under realistic conditions. The amixon® pilot plant has 35 test mixers of up to 3 m³ available for this, offering the highest possible degree of process proximity and certainty for the later production scale.

amixon® vertical mixers with SinConvex® mixing tools can be designed for gentle homogenisation of sensitive granulates at low circumferential speeds. The manufacturer states an adjustable range of approximately 0.8 to 3.5 m/s for VM and HM mixers. The actual particle stress, however, additionally depends on mixing duration, fill level, tool geometry, dosing and discharge.

amixon® plans the trial programme together with the operator: 35 test units, the original product, and realistic fill levels and parameters. Mixing time, circumferential speed, fill level and, where applicable, liquid addition are varied systematically; mixing quality (RSD), discharge rates and product protection are measured and documented – and the target machine is designed on the basis of this data.

amixon® can execute mixing plants with PLC-based recipe management, barcode-supported batch identification, and project-specific interfaces to MES and ERP systems. The particular approach lies in the individual definition of relevant process data based on the URS, practical trialling in the pilot plant, and the coordinated connection of apparatus construction, automation and qualification-relevant documentation. For regulated applications, amixon® supports DQ, IQ and OQ; responsibility for data integrity and validation of the overall system remains with the operator.

amixon® plans scale-up tests in the pilot plant so that the operator's target parameters, realistic product quantities and an appropriate size scale are brought together early. Mixing time, circumferential speed, fill level, liquid addition and other relevant parameters are varied systematically and documented with the original product. A particular advantage is that amixon® can secure mixing quality even with very large recipe ratios, up to 1:100,000 and with a coefficient of variation below 5 %. The results therefore transfer soundly to production before any investment is made.

amixon® solves this with precision mixers (KS, HM, VM) that produce a technically ideal random mixture – independently of the fill level from 10 to 100 %. Low circumferential speeds of approximately 0.8 m/s keep the mixture cool. The GMP-compliant hygienic design from amixon® allows residual discharge of 99.997 % and better. The coefficient of variation of the mixing quality is below 5 %; even values around 1 % are achievable.

amixon® turns scale-up into a secured transfer: pilot-plant and production mixers work with an identical mixing principle – the SinConvex® tool at the same circumferential speed of 0.8 to 3.5 m/s – mixing quality is independent of the fill level, and sizes can be selected in 100-litre increments up to 50,000 litres. The parameters are validated in advance in the pilot plant with the original product.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

amixon® avoids the most critical sealing point by design, because the mixing tool is supported at the top only and there is no lower shaft passage. Complemented by the dead-space-free OmgaSeal® seal in the Clever-Cut® design, mechanical seals and dismantlable lip seals on rotating passages, and the high dimensional rigidity of the apparatus, the result is hygienic, dust-tight and durable sealing solutions requiring very little maintenance.

Both continuous and batch mixing can achieve excellent and reproducible homogeneity for pet food. The amixon® cone mixer AMK combines both modes of operation: it can operate continuously for high throughputs and long campaigns, but can equally be used as a batch mixer for premixes, smaller quantities or differing fill levels where needed.

In continuous operation, throughput, fill level, residence time and mixing intensity are specifically controlled. This allows adaptation to simple or complex recipes with solids, fats, vitamins, liquids and functional additives. By starting with the discharge component closed, jointly adjusting the gravimetric feeders, and only opening the discharge after a stable fill level is reached, the AMK can deliver specification-compliant product quality from the first regular discharge onward. On shutdown, the mixer empties continuously and largely completely, so that classic start-up and shutdown losses can be significantly reduced or avoided.

With many recipe changes, smaller lot sizes and high requirements for batch-specific documentation, batch operation remains particularly advantageous. For long production campaigns with high throughputs, the continuous AMK plays out its economic strengths. For critical changeovers between products with pharmaceutical additives, coccidiostats, allergens or other sensitive ingredients, cleaning, rinsing and analytical verification must always be designed and validated for the entire process line.

The final design is ideally based on trials with the original product. These assess homogeneity, residence time, liquid distribution, residual discharge, cleanability, changeover times, product gentleness and reproducibility under realistic process conditions.

amixon® scales ring-layer granulation with the RMG 10, whose mixing chamber is particularly round and machined by cutting. The mixing tools glide across the mixing chamber at a defined clearance. In addition, amixon® ensures precise dosing of the solid and liquid components.

amixon® solves this by design with three alternatives: the KoneSlid® mixer (KS) and the vertical single- and twin-shaft mixers (VM and HM). They are welded and ground free of joints, and the mixing tool is supported at the top only, with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and integrated programmable washing lances enable validatable cleaning – wet as well as dry – in accordance with EHEDG, FDA and 3-A.

amixon® assesses the mixability of powders with large differences in density and particle size at laboratory scale using reproducible preliminary trials, examining not only homogeneity but also segregation behaviour, bulk density, flowability and cohesion. Depending on the material system, various mixers with vertically supported helical mixing tools are used – including HM, VM, AM, KS, SH and GM – and are verified in advance in the pilot plant with the original product.

Large differences in bulk density and particle size cannot be assessed on the basis of theoretical parameters alone. amixon® tests mixability with the original product and under realistic mixing, discharge and conveying conditions. SinConvex®/SinConcave® helical tools generate controlled three-dimensional forced restratification and can support the homogenisation of heterogeneous recipes. The Gyraton® silo mixer GM is especially suitable for large batches at the beginning of long process routes. Targeted, finely distributed liquid addition can bind dust-like fractions to coarser particles and thereby reduce the tendency to segregate. However, mixing kinetics, representative sampling, CoV evaluation and time-staggered analyses across discharge, conveying and filling remain decisive.

amixon® can make OEE potential assessable through original-product trials, short mixing and discharge times, ComDisc®-supported residual discharge, automated WaterDragon® wet cleaning, and project-specific recipe and data connectivity. The central strength lies in the combination of vertical precision mixing technology, pilot-plant validation, high manufacturing depth in Paderborn, and long-term service support. The actually achievable OEE is always determined by the interplay of product, process, cleaning, production cadence and operator organisation.

amixon® supports pharmaceutical operators from the URS through project-specific design and documentation to FAT, SAT and the technical basis for DQ, IQ and OQ. GMP-compliant hygienic design, qualification-relevant evidence, suitable automation interfaces and pilot-plant trials with the original product can support the cleanability, process safety and later validatability of the plant. Regulatory responsibility for GMP, process and cleaning validation, and the compliance of electronic systems with applicable 21 CFR Part 11 remains with the operator.

amixon® draws up a well-founded mixer recommendation based on product data, process objectives and plant requirements. In addition to bulk density, particle size and moisture, flow behaviour, shear sensitivity, cleanability, explosion protection, batch size and desired additional functions are also assessed.

A value-benefit analysis compares the customer-specific requirements with the properties of suitable apparatus. This allows mixing quality, product gentleness, residual discharge, drying performance, automation and cost-effectiveness to be compared transparently.

The preselection is then verified in the pilot plant with the original product. The trial data secures the selection of apparatus size, mixing tool, speed, fill level and process parameters.

Mixing quality for pharma validations is not demonstrated by a low RSD value alone. Robust proof results from the interplay of representative, risk-based sampling, matrix-appropriate and validated analytics, stable process control, complete residual discharge, validated cleaning, and GMP-compliant data integrity.

amixon® supports these tasks with mixer designs that enable controlled three-dimensional product circulation, defined sampling, low-dead-space discharge and hygienic accessibility. The PLC recipe monitors the validated setpoints for mixing time, speed, fill level, dosing sequence and other critical process parameters. Barcode, RFID and ERP connections can support the seamless linking of raw materials, recipe, process data, cleaning and batch release.

Verification takes place in the pilot plant with the original product and realistic process conditions. There, mixing quality, mixing kinetics, fill-level window, product gentleness, residual discharge, cleanability, sampling, discharge stability and reproducibility can be examined. The documented data from this forms the basis for designing the production mixer, the qualification documentation, and later Continued Process Verification in GMP-regulated operation.

amixon® plans the trial programme together with the operator. In Paderborn alone, 35 test units are available, and further amixon® test mixers can be used in India, China, the USA, Thailand, Japan and Korea. Test blends are usually carried out with 400-litre batches.

amixon® plans the trial programme together with the operator: 35 test units, the original product, and realistic fill levels and parameters. Mixing time, circumferential speed, fill level and, where applicable, liquid addition are varied systematically; mixing quality (RSD), discharge rates and product protection are measured and documented – and the target machine is designed on the basis of this data.

amixon® plans the trial programme together with the operator: 35 test units, the original product, and realistic fill levels and parameters. Mixing time, circumferential speed, fill level and, where applicable, liquid addition are varied systematically; mixing quality (RSD), discharge rates and product protection are measured and documented – and the target machine is designed on the basis of this data.

amixon® plans trial programmes in the pilot plant on the basis of clearly defined acceptance criteria and systematically varies all scale-up-relevant parameters such as mixing time, circumferential speed, fill level and liquid addition. Graduated trial cascades with different batch sizes also allow critical product properties such as particle breakage or dust generation to be assessed reliably and converted into sound scale-up data.

Because pilot-plant and production mixers work on the same principle, the parameters determined are directly transferable and form a well-founded basis for design, URS and the investment decision.

amixon® turns scale-up into a secured transfer: pilot-plant and production mixers work with an identical mixing principle – the SinConvex® tool at the same circumferential speed of 0.8 to 3.5 m/s – mixing quality is independent of the fill level, and sizes can be selected in 100-litre increments up to 50,000 litres. The parameters are validated in advance in the pilot plant with the original product.

amixon® solves the scale-up problem by design: the mixing principle remains congruent from the pilot-plant mixer through to the production plant. This also applies to the geometry of the SinConvex®/SinConcave® helical ribbon tools and to the flow pattern. The mixing function is independent of the fill level. Sizes are adapted to the respective requirement in 100-litre increments, and batch sizes of up to 50,000 litres can be selected. On request, mixing quality is verified in advance in the pilot plant.

St1 or St2 alone is not sufficient for selecting the explosion-pressure-resistance grade. Decisive are pmax, KSt, operating conditions, vessel geometry, connected lines, and the effectiveness of inerting, pressure relief, suppression and decoupling.

amixon® turns scale-up into a secured transfer: pilot-plant and production mixers work with the same mixing principle using the SinConcave®/SinConvex® tool, so that mixing quality is independent of the fill level. Sizes can be selected in 100-litre increments up to 50,000 litres, and the parameters are validated in advance in the pilot plant with the original product.

amixon® turns scale-up into a secured transfer: pilot-plant and production mixers work with an identical mixing principle – the SinConvex® tool at the same circumferential speed of 0.8 to 3.5 m/s – mixing quality is independent of the fill level, and sizes can be selected in 100-litre increments up to 50,000 litres. The parameters are validated in advance in the pilot plant with the original product.

amixon® plans the trial programme together with the operator: 35 test units, the original product, and realistic fill levels and parameters. Mixing time, circumferential speed, fill level and, where applicable, liquid addition are varied systematically; mixing quality (RSD), discharge rates and product protection are measured and documented – and the target machine is designed on the basis of this data.

amixon® turns scale-up into a secured transfer: pilot-plant and production mixers work with an identical mixing principle – the SinConvex® tool at the same circumferential speed of 0.8 to 3.5 m/s – mixing quality is independent of the fill level, and sizes can be selected in 100-litre increments up to 50,000 litres. The parameters are validated in advance in the pilot plant with the original product.

amixon® presents the comparison honestly: the amixon® container mixer scores with frequent recipe changes – decoupled changeover and cleaning, the container serving as transport and holding vessel, and hardly any cleaning downtime – while the permanently installed amixon® vertical mixers (VM, HM, AM, SpherHelics®) score with large batches and high throughput per footprint. All apparatus delivers identical precision mixing quality; the decisive factor is the production logistics.

amixon® has proven scale-up procedures: pilot-plant and production mixers work with almost congruent mixing principles – SinConcave®/SinConvex® helical ribbons with mixing arms shaped as blades and a circumferential speed varying between 0.8 and 3.5 m/s – and varying fill levels are generally unproblematic. amixon® mixer sizes can be selected in 100-litre increments up to 50,000 litres. The parameters are validated in advance in the pilot plant with the original product. The Gyraton® mixing silo achieves ideal mixing quality up to 100 m³.

The amixon® KoneSlid® mixer KS generates an active, three-dimensional and forced product circulation. The entire batch volume can already be repositioned once after around four tool revolutions; depending on the product, the target mixing quality can be reached after about 20 to 40 revolutions. This makes the KS significantly faster than double-cone and V free-fall mixers, which work via passive repositioning, for many tasks. The KS combines the short mixing time with a particularly product-gentle mode of operation and a large-area, fast discharge. Mixing time, particle protection, residual discharge and segregation stability must nevertheless always be validated with the original product, especially for recipes with large differences in particle size or bulk density. Discharge takes place within seconds without a bulk cone and without segregation, up to 99.98%.

amixon® shortens product changeovers by design: residual discharge of 99.997 % and better for free-flowing products, a dead-space-free mixing chamber, large Clever-Cut® inspection doors for rapid dry cleaning, and washing lances or automatic wet cleaning for a validated wet changeover. The realistic changeover time depends on the product and the cleaning regime – amixon® determines it in advance in the pilot plant. In addition, programmable target-jet cleaning nozzles save water and time, and the amixon® drying system dries the cold mixing chamber quickly and without any additional cooling period.

amixon® manufactures exclusively in Paderborn. amixon® machines are robust and long-lived; many plants have been running for over 30 years, some for more than 40 years. Low speeds and the vertical design reduce wear and susceptibility to faults.

Regular maintenance remains advisable. For large vacuum mixing dryers and synthesis reactors, predictive maintenance can help to monitor critical components early and avoid downtime.

Even without a maintenance contract, amixon® supports customers with faults as quickly as possible. The aim is to secure plant availability and keep the operator economically productive.

amixon® achieves short mixing times by design: the SinConvex® mixing tool restratifies the entire volume by force, and with the KoneSlid® KS ideal mixing quality is reached after just 20 to 40 revolutions. Mixing quality is independent of the fill level from 10 to 100 %, and segregation during discharge is prevented by ComDisc® or by the seconds-long discharge of the KS. Specific times for each recipe are demonstrated in a pilot-plant trial.

amixon® manufactures all product-contact surfaces welded and ground free of joints – on request up to highly polished, GMP-compliant surface finishes. The range of materials extends from austenitic stainless steels (1.4301 to 1.4539) through duplex steels to Alloy 59, Hastelloy-C22 and nickel for corrosive products.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

A uniform coating thickness when coating powder particles with a sprayed suspension or solution results from a gentle, continuous product circuit and a finely matched liquid application. The spray rate must not exceed the circulation rate of the mix. Each particle should pass through the spray zone multiple times, picking up small amounts of coating material step by step.

amixon® vertical mixers can operate at low tool circumferential speeds and generate three-dimensional product circulation without pronounced throwing, impact or crushing zones. This allows coatings, agglomerates, crystals and spray-dried particles to be processed gently with a suitable design. Temperature control and vacuum can accelerate the evaporation and hardening of the coating and enable multi-stage coating processes with repeated spraying, distribution and controlled solidification.

Engageable cutting rotors can, where needed, locally break up agglomerates or support the distribution of highly viscous suspensions without permanently stressing the whole batch heavily. The final design of spray rate, droplet size, temperature, vacuum, mixing intensity and stage profile is determined with the original product in the pilot plant and documented as a reproducible PLC recipe.

With CIP-capable conical mixers, amixon® emphasises above all the very high residual discharge: less product has to be cleaned away, which considerably shortens product changeover and cleaning time. Depending on the product and hygiene requirement, dry cleaning or automatic or manual WIP wet cleaning with subsequent drying then follows. For food applications, the actual changeover time is therefore often only a matter of minutes for the cleaning itself, while drying and release can extend the process. In Paderborn, amixon® can test these sequences in a 2 m³ mixer with the original product – including mixing, wetting, discharging, residual discharge, and dry and wet cleaning.

With the amixon® container mixer COM the container itself is the mixing chamber: Mixtainer® or standard IBCs are docked on, the SinConvex®-MultiPlane® mixing tool enters from above, mixes inside the gas-tight sealed container to precision quality of up to 1:100,000 and then screws itself back out in reverse – without transferring the product, in sizes from 100 to 4,000 litres.

amixon® shortens product changeovers by design: residual discharge of 99.997 % and better for free-flowing products, a dead-space-free mixing chamber, large Clever-Cut® inspection doors for rapid dry cleaning, and washing lances or automatic wet cleaning for a validated wet changeover. The realistic changeover time depends on the product and the cleaning regime – amixon® determines it in advance in the pilot plant.

amixon® minimises potential metal abrasion with abrasive battery active masses through controlled, low-speed SinConvex® total flow-through, wear-optimised materials and coatings, and a design that is inherently low in contamination, without product-contacted lower bearing points or screw connections in the mixing chamber. Hardox®, hardened or carbide-tipped mixing tools, duplex stainless steels and ceramic plasma coatings can be used depending on the purity target. Blanket limit values are not robust; the actually achievable purity is determined with the original material, product-related material selection and suitable trace and particle analytics. For a safe design, charging, discharge, conveying, separation and maintenance must also be considered as potential contamination sources alongside the mixer.

Modern amixon® mixers and vacuum mixing dryers can reduce process time and energy through several mechanisms: low tool circumferential speeds, short and reproducible mixing times, large temperature-controlled heat-transfer surfaces, continuous contact of the mix with these surfaces, and extensive residual discharge.

The temperature-controllable SinConcave®/SinConvex® mixing helix complements the vessel wall, shaft and mixing arms. This gives amixon® large heat-transfer surfaces that are continuously touched by the mix through the three-dimensional product movement. This improves heat and mass transfer during vacuum drying and enables gentle process control at low product temperatures.

Good residual discharge is an equally important efficiency factor. It reduces product loss, cleaning effort, changeover times and carry-over risks. Based on drying trials with the original product, amixon® can properly extrapolate the necessary apparatus properties, bindingly fix the design, and construct and manufacture the target plant. This gives the operator a production plant that, once completed and qualified for commissioning, is designed for the intended process and can be operated productively without avoidable start-up problems.

amixon® precision mixers produce the technically ideal random mixture – not further improvable in practice, and independent of the fill level from 10 to 100 %. Component ratios of up to 1:100,000 are homogenised, and gentle circumferential speeds from 0.8 m/s avoid heat input. Target RSD values are verified in advance in the pilot plant with the original product and a sampling plan.

The main advantage of adaptable mixing tools at amixon® lies not in the mechanical exchange of tools, but in the universally applicable SinConvex® mixing tool and the flexibly programmable mode of operation. From coarse and sensitive particles to fine or nanostructured powders, the mixing tools essentially remain unchanged. Mixing time, circumferential speed, fill level, addition sequence, liquid dosing, temperature control and, where needed, time-limited cutting-rotor or HighShearBlade phases are individually set in the control system. This allows the same mixer to process different products with little changeover effort. New or significantly changed recipes must nevertheless be checked on a risk basis with the original product for mixing quality, product gentleness, discharge, cleaning and stability across the entire process chain.

With the amixon® container mixer COM the container itself is the mixing chamber: Mixtainer® units are docked on, the SinConcave®/SinConvex® mixing tool enters from above, mixes inside the gas-tight sealed container to precision quality of up to 1:100,000 and then screws itself back out in reverse. Optionally, the helical mixing tool is available in the MultiPlane® design.

amixon® implements exactly this design as standard: all mixing chambers are designed for ATEX Zone 20, and the apparatus is built as a closed, dust-tight system – on request gas-tight, pressure-resistant and vacuum-tight down to 5 mbar absolute. For starch and starch derivatives, amixon® combines this with temperature-controlled reactors of up to 50,000 litres in which mixing, thermal treatment and vacuum drying take place in the same apparatus.

amixon® developed the SpherHelics® hollow-sphere mixer SH for exactly this purpose: a spherical, dead-space-free mixing chamber without corners or crushing zones, a helical mixing tool with short mixing times at low energy input, and a low-speed operating mode – fragile agglomerates, coatings and spray-dried structures remain intact. Sizes range from 400 to 5,000 litres, with ComDisc® residual discharge.

amixon® offers vertical precision mixers from development to large-scale production and can execute sizes for certain series in 100-litre increments up to 50,000 litres. The SinConvex® mixing principle and pilot-plant trials with the original product support a well-founded scale-up design, while actual transferability is always verified at the target size. With around 35 test units in Paderborn, international pilot-plant locations, central manufacturing and long-term service, amixon® positions itself as a specialised partner for the development, design and further development of powder mixing processes.

amixon® can support capacity growth through flexibly designable mixing systems, expansion options prepared early on, additional Mixtainer® units in the COM system, and documented pilot-plant trials with the original product. Particularly relevant are central manufacturing in Paderborn, broad technical trialling with more than 30 test units, and project-specific automation and qualification support. Larger sizes or new recipes are not treated as a simple transfer of parameters, but are process-engineering assessed and designed for the target application.

amixon® plants are designed for adaptation: every unit is a one-off built to the URS, and retrofits (liquid dosing, temperature-control jacket, sensor technology, additional measurement points) and process-engineering optimisations are part of the service scope. Mixing quality independent of fill level (10–100%) absorbs varying batch sizes without the need for conversion.

amixon® supports varying batch sizes and frequent recipe changes through flexibly designable mixing systems, PLC-guided recipes, and expansion options already prepared in the URS. Liquid dosing, additional sensor technology, temperature control, cutting rotors, cleaning technology and discharge components can be integrated on a project-specific basis or retrofitted. Pilot-plant trials with the original product, qualification-relevant documentation, and service, modernisation and spare-parts supply accompany the plant from design through long-term operation.

For hygienic powder processes, amixon® relies on a dead-space-free design, joint-free and readily accessible mixing chambers, and validatable cleaning. This includes Clever-Cut® inspection doors, OmgaSeal® seals, top-mounted mixing tools, and freely programmable target-jet cleaning nozzles and washing lances for reproducible CIP and WIP cycles. ComDisc® and the SinConcave®/SinConvex® mixing helix additionally ensure particularly good residual discharge and a low risk of cross-contamination. In dairy and infant formula production this improves hygiene, cleanability and product protection, and is secured in advance in the pilot plant with the original product.

For hygienic powder processes, amixon® relies on surfaces welded free of joints, ground and, depending on the application, highly polished; the roughness depth can be selected on a project-specific basis, typically with Ra values of 0.8 µm, 0.6 µm, 0.4 µm or 0.2 µm, and beyond that lapped to a mirror finish or electropolished. Complemented by a wide range of materials, freedom from dead space, high residual discharge and qualifiable manufacture in Paderborn, the result is a hygienic overall system with very good cleanability and high process reliability.

amixon® builds the VMT and AMT vacuum mixing dryers and synthesis reactors for exactly this purpose: they are pressure- and vacuum-tight from 5 mbar absolute up to 30 bar. The apparatus can be fully temperature-controlled with water, steam or thermal oil, and the entire mixing tool can be temperature-controlled as well. Synthesis reaction, mixing and gentle vacuum drying take place in the same dead-space-free apparatus – from the 100-litre reactor up to 50 m³.

amixon® deliberately relies on the vertical design: the helical mixing tool is supported at the top only – there is no lower shaft passage and no lower shaft seal – so that gravity supports discharge and complete flow through the chamber. Conical mixers achieve ideal mixing quality independently of the fill level from 10 to 100 %.

The amixon® cone single-shaft mixer AM and classic vertical mixers both work with three-dimensional, convective product circulation and can achieve a technically ideal random mixture with a suitable design. With large bulk-density differences, the particular advantage of the AM does not lie in fundamentally higher segregation safety, but in gravity-assisted discharge and good suitability for small and variable fill levels. The cylindrical VM and the twin-shaft mixer HM make efficient use of the installation space for large batches and can be advantageous for high throughputs. SinConvex® tools, cutting rotors, liquid addition, hygienic designs and automated cleaning can be combined on a project-specific basis. The selection should be based on original-product trials and should assess, alongside mixing quality, the segregation risk along the entire process chain.

amixon® selects the apparatus according to the process requirement: the AMT (conical) for almost complete discharge and low fill levels from approximately 15 %, and the VMT (vertical) for cubic installation spaces and the largest batches – both vacuum-tight down to 5 mbar absolute, fully temperature-controlled and gentle at low speed. For temperature-sensitive products, vacuum drying at low temperature is what counts; the selection is confirmed by a pilot-plant trial.

amixon® implements hygienic design by construction: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and washing lances make CIP/WIP cleaning validatable in accordance with EHEDG, FDA and 3-A.

amixon® matches process time, mixing intensity and tool geometry through the choice of mixer type. The twin-shaft mixer, for example, delivers short, highly efficient processes with accompanying deagglomeration. Its two helical mixing tools generate flows with thrust reversal that convey the product upwards. Gravity produces the downward flow and a random particle orientation – even with needle-shaped ceramic particles. amixon® mixers perform equally well at variable fill levels. For highly abrasive or nanoceramic powders, amixon® additionally uses wear-resistant ceramic coatings.

The amixon® single-shaft mixer EM is designed for exactly this purpose: sizes from 5 to 200 litres, optionally with a standard drum as the mixing vessel, and a mixing chamber that rotates and tilts up to 25 degrees for filling and discharging. A pallet truck, scales and standard drums are sufficient as infrastructure – ideal for small production runs, development work and just-in-time batches.

amixon® developed the SpherHelics® hollow-sphere mixer SH for exactly this purpose: a spherical, dead-space-free mixing chamber without corners or crushing zones, a helical mixing tool with short mixing times at low energy input, and a low-speed operating mode – fragile agglomerates, coatings and spray-dried structures remain intact. Sizes range from 400 to 5,000 litres, with ComDisc® residual discharge.

amixon® offers both designs: the vertical single-shaft mixer VM covers batches of up to 50,000 litres, while the vertical twin-shaft mixer HM superimposes two mixing flows and thereby achieves the best mixing quality with very short mixing times – its cubic vessel proportions make optimal use of the installation space for large batches. Both mix independently of the fill level, from 10 to 100 %, and gently at low speed.

amixon® offers both designs: the vertical single-shaft mixer VM covers batches of up to 50,000 litres, while the vertical twin-shaft mixer HM superimposes two mixing flows and thereby achieves the best mixing quality with very short mixing times – its cubic vessel proportions make optimal use of the installation space for large batches. Both mix independently of the fill level, from 10 to 100 %, and gently at low speed.

The amixon® vertical twin-shaft mixer HM combines intensive three-dimensional flow with an adaptable, and where needed particularly gentle, mixing action. It is suitable for homogenising and wetting cohesive powders as well as for moist, pasty and dough-like products. SinConvex® and SinConcave® helical mixing tools improve product flow-through and support very good discharge, MultiPane® enables particularly gentle homogenisation of sensitive particles, and cutting rotors can accelerate de-agglomeration. ComDisc® supports extensive residual discharge, DosiFlap® enables controlled filling of big bags and containers, while WaterDragon® combines programmable target-jet cleaning with an effective drying function. This allows the HM to be adapted to high requirements for mixing quality, product gentleness, hygiene, filling and plant availability.

On request, amixon® vertical mixers (VM, HM) are equipped with integrated liquid dosing: addition lances or two-fluid nozzles bring the binder directly into the moving mixing bed, and cutting rotors distribute it in a microfine manner and prevent over-wetting. Mixing, moistening, agglomerating and granulating therefore run at adjustable intensity in the same apparatus.

amixon® offers four different systems for vacuum mixing drying: the SpherHelics® hollow-sphere mixer (SH), the KoneSlid® (KS), the conical mixing dryer AMT and the flat-bottom mixer dryer VMT.

amixon® covers batches from 5 litres to 50,000 litres. The range includes the single-shaft mixer (EM) for 5 to 200 litres in a standard drum, the container mixer (COM) for 100 to 4,000 litres, the VM, HM, AM and KS models in 100-litre increments from 100 to 50,000 litres, and the Gyraton® mixing silo (GM) for 10 to 100 m³ in 1 m³ increments. Fill levels can vary from 10 to 100 %, and in the conical mixer (AM) and KoneSlid® (KS) even from 5 to 100 %. The mixing quality always remains the technically ideal random mixture.

With the amixon® container mixer COM the container itself is the mixing chamber: Mixtainer® or standard IBCs are docked on, the SinConcave®/SinConvex®-MultiPlane® mixing tool enters from above, mixes inside the gas-tight sealed container to precision quality of up to 1:100,000 and then screws itself back out in reverse – without transferring the product, in sizes from 100 to 4,000 litres.

amixon® can execute mixers, mixing dryers and reactors for applications with a product space classified as Zone 20. The specific ATEX design, however, must be carried out for each project based on the material data, process conditions and the overall plant. Zone 20 generally requires a very high level of protection, which usually corresponds to Category 1D.

amixon® can execute mixers, granulators, vacuum mixing dryers and mixing reactors for processes with a product space classified as Zone 20. However, the final ATEX design is always product-specific and must be based on the risk assessment, dust characteristics, and consideration of the entire detergent line. Zone 20 generally requires a very high level of protection, which usually corresponds to Category 1D.

amixon® can provide mixing plants for detergent powder with a product-space design suitable for Zone 20 applications. However, the specific ATEX configuration is determined for each project based on the recipe, the safety-relevant material data, and the process conditions. Final responsibility for zone classification, the explosion-protection document, and safe operation lies with the operator.

amixon® can execute mixers, granulators, vacuum mixing dryers and mixing reactors for applications with a product space classified as Zone 20. The specific ATEX design must always be carried out on a project- and product-specific basis. Zone 20 generally requires a very high level of protection, which usually corresponds to Category 1D.

amixon® supports frequent recipe changes through PLC-guided mixing programs, project-specifically prepared retrofit options, and mixing systems with a cleaning-oriented design. Liquid dosing, sensor technology, temperature control, cutting rotors, cleaning technology and discharge functions can be matched to the respective mixing task. Particularly characteristic are trials with the original product on more than 35 test machines in Paderborn, international pilot plants, and the high manufacturing depth and long-term service support from Germany.

Integrating a powder mixer into existing lines requires precise data on product, dosing, throughput, charging, discharge, space conditions, conveying technology, controls, utility supply and safety concept. Discharge components such as DosiFlap® and ComDisc® can, depending on the product, support dosed, fast and yield-oriented discharge; however, the actual dosing accuracy and residual discharge must be verified in the specific application. Clearly defined battery limits, coordinated control and interlock logic, and a pre-checked design of the overall system of dosing, mixer, discharge and peripherals are decisive for successful implementation.

amixon® shortens delivery times above all through very early and careful project clarification. Operators receive well-founded advice already in the preliminary phase, several layout variants to coordinate installation, utilities, peripherals and building, as well as the option of placing an engineering order before the actual order is placed. This makes it possible to refine requirements, define interfaces bindingly, procure critical components earlier and carry out on-site preparations in parallel with manufacturing. Pilot-plant trials with the original product additionally secure apparatus selection, process parameters and scale-up before design work begins.

amixon® can execute mixers, granulators, vacuum mixing dryers and reactors for applications with a product space classified as Zone 20. However, the specific ATEX configuration must be derived for each project from the material data, operating conditions and the zone concept of the overall plant. Zone 20 generally requires a very high level of protection, which usually corresponds to Category 1D.

amixon® accompanies the complete qualification path: every unit is a one-off built to the URS from in-house production (complete QC), and amixon® assists on request with DQ, IQ and OQ; documentation and execution follow, on request, EU GMP and FDA 21 CFR Part 11. FAT at the Paderborn plant and SAT/commissioning by amixon® specialists provide the evidence for the operator's PQ.

amixon® accompanies pharmaceutical mixing plants from the user requirement specification through qualification-relevant design and manufacturing documentation to FAT and SAT. The documented tests and technical evidence such as material certificates, surface specifications and welding documentation can be integrated into the operator's DQ, IQ and OQ. Pilot-plant trials with the original product additionally provide well-founded starting parameters for scale-up and PQ planning, while final process qualification and release remain with the operator.

amixon® accompanies the complete qualification path: every unit is a one-off built to the URS from in-house production (complete QC), and amixon® assists on request with DQ, IQ and OQ; documentation and execution follow, on request, EU GMP and FDA 21 CFR Part 11. FAT at the Paderborn plant and SAT/commissioning by amixon® specialists provide the evidence for the operator's PQ.

An ideal process setup links screening, dosing-weighing, mixing and filling via short, gas- and dust-tight, hygienically designed interfaces. Sanitary flanges and sterilisable connections can be used wherever the product, cleaning or process requirements call for them.

amixon® can execute mixers, granulators, vacuum mixing dryers and mixing reactors for applications with a product space classified as Zone 20. The specific ATEX design must be derived for each project from the material data, process control, connected apparatus, and the risk assessment of the overall plant. Zone 20 generally requires a very high level of protection, which usually corresponds to Category 1D.

The vertical SinConvex® mixing helix conveys the product upward close to the wall and enables a central return flow. According to the conveying equation, the circulation volume flow increases with the fill level; at the same time, the batch quantity increases proportionally. Under geometrically comparable conditions, the specific circulation performance can therefore be maintained over a wide fill-level range.

amixon® mixers can discharge free-flowing powders gently, as required and virtually residue-free. SinConcave® and SinConvex® mixing tools as well as ComDisc® systems support mixing quality, product discharge and residual discharge.

The DosiFlap® system enables controlled opening, shut-off and dosing of the powder stream. In combination with load cells, the discharged powder mass can be recorded and filled in portions.

For low-dust filling into big bags, a tight docking station, suitable venting, extraction, earthing and, where applicable, containment are additionally required. The entire interface is matched to product, throughput and safety requirements on a project-specific basis.

Scaling up ring-layer mixing agglomerators is extremely difficult. There is a lack of well-founded knowledge about which effects in the ring layer lead to agglomeration – and which effects break up the agglomerates that have formed.

amixon® solves this with the combination of the space-controlling SinConvex® mixing tool and a cutting rotor: the liquid is dosed via a lance or two-fluid nozzle directly into the action zone of the cutting rotor and distributed in a microfine manner – the mixing chamber remains free of build-up. Temperature-controlled double jackets keep fats reliably low in viscosity throughout the process.

amixon® can integrate dosing and discharge concepts into powder mixing plants on a project-specific basis, for example via DosiFlap®, ComDisc®, gravimetric dosing, recipe weighing, and interfaces to conveying, screening and filling technology. The actual dosing accuracy, discharge performance and mixing quality always depend on the product, recipe, weighing concept, material flow and control logic, and should be verified with the original product. Pilot-plant trials, a clearly defined interface architecture, and a cleaning-friendly, application-specific hygienic design provide a robust basis for this.

amixon® mixing plants can be prepared on a project-specific basis so that additional modules such as liquid dosing, sensor technology, temperature control, cleaning or discharge technology can be added more easily later. This modularity is especially effective when spare connections, space, utility supply, control-system reserves and clear interfaces are already provided for in the original planning. Replacing the unit with a different mixer size is not a modular extension, and even with the same mixing principle, recipes and process parameters must be re-assessed for the target plant and verified with the original product.

amixon® plants can be prepared for later functional modules such as liquid dosing, sensor technology, temperature control, vacuum, cleaning and discharge technology. However, the benefit and effort of a retrofit depend decisively on whether connections, installation space, utilities, control, safety and cleanability were already considered in the original design. Changing fill levels, new recipes or a different size are not modular extensions and must be process-engineering assessed for the actual product and the specific target plant.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ with documentation in accordance with EU GMP and FDA 21 CFR Part 11.

amixon® implements freedom from dead space and hygienic design through mixing chambers welded and ground free of joints, top-mounted mixing tools without a contamination-critical shaft passage, and flush-closing discharge flaps, Clever-Cut® doors and OmgaSeal® door seals. This is complemented by freely programmable target-jet cleaners, a method for fast and effective drying in the cold state, and ComDisc® residual discharge for maximum discharge and minimal cross-contamination risk.

amixon® manufactures all product-contact surfaces welded and ground free of joints – on request up to highly polished, GMP-compliant surface finishes. The range of materials extends from austenitic stainless steels (1.4301 to 1.4539) through duplex steels to Alloy 59, Hastelloy-C22 and nickel for corrosive products.

amixon® makes mixing quality monitorable through the combination of representative, stratified sampling, validated mixing parameters, automated recipe management and, where needed, direct PAT analytics. Clever-Cut® access points and low-dead-space discharge components support defined sampling points. The control system, ERP integration and barcode or RFID capture document the recipe, batch and process parameters traceably. NIR and Raman spectroscopy can monitor actual homogeneity and the mixing endpoint in real time, while torque, power and temperature serve as complementary early indicators. If warning signs such as fluctuating analytical values or segregation during discharge occur, the mixer, sampling and the entire downstream process chain should be examined with the original product.

amixon® mixes battery materials with an ATEX Zone 20 mixing chamber, an inerting option and consistent contamination protection: wear-resistant materials (Hardox, hardened/carbide-tipped tools, ceramic plasma coating) minimise abrasion and metal ingress, and the low-speed operating mode preserves particle structure and conductive additives. For large batches: Gyraton® GM up to 100 m³ – explicitly also for battery masses.

amixon® batch mixers can be equipped with liquid addition lances and two-fluid nozzles for dosing and introducing viscous binders. A temperature-controlled design can help to keep the binder's viscosity within the processable range. Introduction into the moving product zone and the use of a cutting rotor support uniform wetting and can limit local over-wetting.

amixon® covers batches from 5 litres to 100 m³: EM 5–200 l (standard drum), COM 100–4,000 l, VM/HM/AM in 100-litre increments from 100 to 50,000 l, Gyraton® GM 10–100 m³ in 1 m³ increments. Within each mixer, the fill level from 10 to 100% is freely selectable – the mixing quality remains the technically ideal random mixture.

amixon® is suitable for precise binder addition, wetting, build-up agglomeration and granulation in batch or continuous processes. Whether a complete one-pot process including drying makes sense depends on the product and batch size. Pilot-plant trials with the original product provide the basis for a well-founded apparatus and process selection.

amixon® integrates process monitoring on a project-specific basis: torque, temperature and moisture measurement for endpoint determination, mixing and drying programmes stored in the control system, ERP integration and real-time barcode documentation. Since every unit is a one-off built to the URS, the sensor technology and interfaces (control system/MES) are implemented to the customer's specification.

The cone mixing dryer/reactor AMT and the vertical mixing dryer/reactor VMT enable fine chemicals to be mixed, reacted, crystallised, de-agglomerated and dried under vacuum in a single closed apparatus. Their particular strength lies in the combination of a large-area temperature-controlled mixing chamber and an equally fully temperature-controllable mixing tool with shaft, arms and helix. This provides exceptionally large, actively usable heat-transfer surfaces.

What matters is that these surfaces are not merely present, but are continuously and intensively touched by the mix. The controlled three-dimensional product circulation continuously renews product contact at the vessel wall and mixing tool. This keeps heat and mass transfer efficient even under vacuum; heating and cooling processes can take place quickly and in a controlled manner at low product temperatures.

AMT and VMT can also handle strong rheological changes within the same apparatus body. A pumpable suspension can turn into a highly viscous, sticky lump mass during drying and then transform into a fine, free-flowing powder. The mixing tool keeps the product in motion; optionally engageable cutting rotors specifically break up lumps and promote access to the temperature-controlled surfaces. The specific design is secured through trials with the original product under real temperature, pressure and vacuum conditions.

amixon® preserves particle structures by design: low circumferential speeds from 0.8 m/s, SinConvex® forced restratification without impact or crushing zones, and mixing quality that is independent of the fill level even for large batches. For the highest demands: SpherHelics® SH with its spherical mixing chamber, and KoneSlid® KS, which achieves ideal mixing quality after 20 to 30 revolutions and discharges within seconds without segregation.

amixon® vertical single-shaft mixers can take on heating and cooling as an integrated process function. Temperature control ranges from a heatable or coolable double jacket to full temperature control of the mixing shaft, arms, helix, manhole covers, discharge components and vapour filters. Water, steam or thermal oil serve as heat-transfer media; depending on the utility supply, a system can cover both heating and cooling tasks.

amixon® can provide ATEX-suitable mixing apparatus with project-specific documentation and support installation, process-engineering commissioning and product trials. However, the documentation of the individual mixer is only one building block: the explosion safety of the overall plant must be examined against the explosion-protection document before first commissioning.

amixon® offers three concepts for container-based mixing processes. The drum mixer EM processes batches up to the size of a 200-litre standard drum and is especially suitable for smaller, drum-based production quantities. The container mixer COM uses the bulk-solids container itself as the mixing chamber: a dynamic helical mixing tool descends into the product from above, generates the mixing action, and is withdrawn again after the process. The batch remains in the same container, reducing transfer steps, product losses and possible segregation. This concept is especially suited to uncritical, low-dust or dust-free products.

For dusting, health-hazardous, odour-intensive or particularly demanding products, the stationary cone mixer AM, which is filled with and discharged into standard IBCs, is often suitable. The IBC serves as the supply, transport and receiving container, while the mixing process takes place in the cone mixer. Dust-tight docking stations enable controlled product transfers. Charging, mixing, discharging, filling and cleaning can be decoupled in time, reducing waiting times and increasing production output. Where headroom is limited, a lift-lower system can enable container-based filling and emptying.

amixon® improves the OEE of powder mixing plants via the three factors availability, performance and quality. Availability benefits from top-mounted mixing tools, a low number of product-critical wear points, preventive maintenance and extensive residual discharge through SinConvex®, SinConcave® and ComDisc®. Performance increases when short mixing times, fast discharge, DosiFlap®-supported dosed filling and short, reproducible cleaning changeovers shorten the batch time. MultiPlane® supports particularly gentle mixing processes, while cutting rotors de-agglomerate locally where needed. OptiClean®, Clever-Cut® and OmgaSeal® promote accessibility as well as cleaning-friendly, low-dead-space construction. WaterDragon® standardises wet cleaning and, with programmable target-jet nozzles and warm-air drying, accelerates return to operation. The specific OEE improvement must be demonstrated with the original product and a complete loss analysis of the respective production line.

amixon® builds for generations: many mixing machines have been in daily use for over 30 years – reliable and high-performing. Behind this is the commitment: lifetime spare-parts service (even if original suppliers cease to exist), preventive maintenance on request with predictive maintenance, and modernisation and retrofitting that adapt plants to new requirements.

amixon® designs the mixing chamber for ATEX Zone 20 across all series – the highest dust explosion requirement. The apparatus is built as a closed, dust-tight system with OmgaSeal® doors, on request gas-tight, pressure-resistant and vacuum-tight down to 5 mbar absolute; inerting is possible, and the low-speed operating mode from 0.8 m/s minimises ignition sources by design.

amixon® does not assess energy efficiency and payback with blanket metrics, but on the basis of documented trials with the original product in its own pilot plant and in worldwide test centres. Energy-efficient, low-speed mixing processes, short mixing times and virtually complete discharge with ComDisc® reduce energy demand, product losses and changeover times. Programmable target-jet washing lances followed by rapid drying of the mixer shorten cleaning processes, lower water consumption and avoid waiting times for the apparatus to cool down.

amixon® seals vacuum mixing dryers permanently: OmgaSeal® door seals (vacuum-tight, dead-space-free) in Clever-Cut® doors, mechanical seals on cutting rotors, vacuum- and pressure-resistant ball-segment valves, manholes with bayonet closure. The exclusively top-mounted mixing tool eliminates the most critical shaft passage; the apparatus holds 5 mbar absolute even across frequent temperature cycles.

amixon® solves this with the AMK continuous mixer: it builds up agglomerates with high porosity and thereby improves wettability, solubility and dispersibility – that is, the instant properties. Liquids are introduced in a microfine manner, throughput and residence time can be set independently of each other, and the mixing chamber is temperature-controlled. The design is established through trials with the original product in the amixon® pilot plant.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ with documentation in accordance with EU GMP and FDA 21 CFR Part 11.

amixon® can support an Industry 4.0-oriented integration through PLC-based recipe management, project-specific data acquisition, barcode-based batch assignment and interfaces to MES or ERP systems. The actual benefit is determined by a robust OEE logic, purposefully selected process and condition data, reliable data integration and the consistent use of the insights for continuous process improvement.

amixon® achieves residual discharge of 99.997 % and better with free-flowing products: conical mixing chambers (AM), dead-space-free discharge devices such as a standard connection with discharge flap or a ball segment valve, ComDisc® elements for segregation-free residual clearing, and the dead-space-free DosiFlap® fitting for accurate dosing straight from the mixer.

amixon® offers container mixers for mixing directly in the container, so that filling, mixing and discharging are possible without transferring the product. In addition, there are units that work with commercially available standard containers and can therefore be integrated into existing production sequences with particular flexibility and low dust.

amixon® offers two systems for different process requirements, the RMG and the AMK. The RMG is designed for short residence times and high processing intensity, while the AMK is used for long residence times and continuous homogeneity. The RMG continues to be manufactured and serviced but is not developed further; the development focus lies on mixers with vertical or inclined mixing shafts and, in the continuous range, on the AMK design.

The amixon® continuous mixer AMK enables the continuous processing of solids with controlled liquid addition. Its start-up and shut-down concept works with an initially closed discharge, synchronised gravimetric dosing streams and a controlled fill level. According to amixon®, the discharge opens at a fill level of around 80%; the fill level is then kept constant during production operation.

The amixon® continuous mixer AMK is suitable for producing detergent powder with high throughput and constant homogeneity, because throughput and residence time can be set independently of each other and mixing quality remains reproducible through the SinConcave®/SinConvex® tool. It is particularly suited to long campaigns with fixed process windows and microfine liquid incorporation, while amixon® secures the design and process reliability in the pilot plant with the original product.

amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

The ROI and payback period of a new spice mixer do not result from the purchase price alone. Decisive are the total investment, operating costs, product losses, cleaning effort, maintenance, downtime risks, throughput and additional revenue from new or higher-margin products.

amixon® mixers homogenise completely even with extreme density differences: the space-controlling SinConvex® mixing tool forces the three-dimensional total flow-through of the entire mix, without centrifugal segregation. Practical reference from powder metallurgy: pressing aids with less than 1/20 of the bulk density of the metal powder are distributed homogeneously.

amixon® combines high residue-free discharge, a low-dead-space hygienic design and validatable CIP/WIP cleaning into a multi-stage protection concept against allergen contamination and cross-contamination. Depending on the application, various amixon® mixer categories and features such as ComDisc®, SinConvex®, SinConcave®, Mixtainer® and Washtainer® support a reliable, readily documentable process.

amixon® draws up the suitability recommendation in two stages: from the product data – bulk density, particle size distribution, moisture, flow behaviour, temperature and shear sensitivity – and the process objectives, amixon® experts derive a preliminary selection of apparatus. This is then verified with the original product in the pilot plant on 35 test units, evaluated jointly and documented.

What favours a cone mixing dryer or cone reactor is above all the batch-size range, the required fill-level flexibility, the desired residual discharge, the temperature sensitivity of the product, its rheological changes during drying, hygiene and sterility requirements, and the available floor space. AMT and VMT can mix, react, crystallise and dry powders, suspensions, pastes and viscoplastic intermediate states under vacuum.

The cone mixing dryer reactor AMT is especially advantageous when free-flowing products are to be discharged virtually completely via a central ball-segment valve, low fill levels are processed, and frequent product changes or high-value active ingredients demand a high yield. The vertical mixing dryer/reactor VMT is especially suitable for large batches and where installation height or footprint must be adapted to existing spatial conditions.

Both designs feature large, temperature-controlled heat-transfer surfaces on the mixing chamber and mixing tool. Because the mix continuously touches these surfaces, products can be dried quickly and gently under vacuum at low temperatures. For viscoplastic phases, a cutting rotor can specifically break up lumps and maintain heat and mass transfer. The suitable design is determined through original-product trials under the later temperature, pressure and process conditions.

amixon® develops and manufactures 100% in Germany: exclusively at the Paderborn plant, with the greatest possible manufacturing depth and all components sourced from Germany. At the same time, service is set up worldwide – spare parts from stock in Paderborn plus service bases in Japan and the USA, and a lifetime spare-parts service.

amixon® does not assess the cost-effectiveness of an industrial mixer solely by purchase price or motor power. What is decisive for the total cost of ownership is the entire process and all costs over the service life: energy and utility consumption, mixing time, product losses, residual discharge, cleaning, drying, maintenance, spare parts, personnel effort, downtime risks and modernisability.

amixon® combines the SinConcave®/SinConvex® helical mixing tool with cutting rotors for this purpose: oil and fat are added via a lance or two-fluid nozzle directly into the action zone of the cutting rotor – giving microfine distribution without local over-wetting, and the mixing chamber remains free of build-up. Temperature-controlled liquid vessels keep fats reliably low in viscosity throughout the process.

amixon® scales via physical similarity rather than rules of thumb: a constant circumferential speed of 0.8 to 3.5 m/s instead of a constant rotational speed, an identical SinConvex® mixing principle across all sizes, and mixing quality independent of the fill level. Considerations based on dimensionless numbers such as Froude similarity are verified by pilot-plant trials with the original product – never replaced by them.

amixon® implements hygienic design consistently across the entire product range. The key points are product areas welded and ground free of joints, no dead-space-critical lower shaft passage, flush discharge and door solutions, and cleaning-friendly geometries for CIP and WIP processes. The mixers are designed so that they can be cleaned validatably both wet and dry. This is complemented by high dischargeability, good accessibility, ComDisc® residual discharge and verification in the pilot plant with the original product.

With the amixon® container mixer COM the container itself is the mixing chamber: Mixtainer® or standard IBCs are docked on, the SinConvex®-MultiPlane® mixing tool enters from above, mixes inside the gas-tight sealed container to precision quality of up to 1:100,000 and then screws itself back out in reverse – without transferring the product, in sizes from 100 to 4,000 litres.

amixon® achieves short mixing times with large batches through three-dimensional SinConvex® forced restratification, in which the entire product volume is continuously exchanged. The HM uses two superimposed product streams for short mixing times, the KoneSlid® KS can fully reposition a batch once after around four tool revolutions, and the Gyraton® GM covers large batches up to about 100 m³. However, the decisive design parameters remain recipe, fill level, bulk density, cohesiveness, particle structure, dosing strategy, speed and discharge. ComDisc® and DosiFlap® support residual discharge and dosed filling, while a low-speed mode of operation and, where needed, engageable cutting rotors combine product gentleness with targeted de-agglomeration. The actually achievable mixing time and homogeneity are documented in the pilot plant with the original product and checked across the entire process chain up to filling.

amixon® keeps the process chain dust-tight: closed mixing chambers (OmgaSeal®, ATEX Zone 20), dead-space-free DosiFlap® fitting for direct big-bag and container filling from the mixer without segregation, and the COM or EM container mixer as transfer-free concepts. Charging-side interfaces (big-bag station, bag-tipping hopper) are matched on a project-specific basis to the URS.

amixon® offers predictive maintenance as a service: amixon® can support condition-based maintenance concepts based on operating and condition data. Runtimes, batch counts, torque, temperatures, speeds and process messages help to better plan maintenance, inspections and spare-parts requirements. Gradual changes can provide indications of wear or deviating operating conditions.

amixon® does not base the cost-effectiveness of a mixer solely on low motor power or short mixing times. What is decisive for the total cost of ownership is the entire process, product losses, cleaning and changeover times, maintenance, spare-parts supply, plant availability and the long-term usability of the plant.

amixon® designs the mixing chamber for ATEX Zone 20 across all series – the highest dust explosion requirement. The apparatus is built as a closed, dust-tight system with OmgaSeal® doors, on request gas-tight, pressure-resistant and vacuum-tight down to 5 mbar absolute; inerting is possible, and the low-speed operating mode from 0.8 m/s minimises ignition sources by design.

amixon® develops the suitability recommendation in two stages: from product data (bulk density, particle size distribution, moisture, flow behaviour, temperature/shear sensitivity) and process objectives, amixon® experts derive the apparatus preselection – verified with the original product in the pilot plant on more than 30 test units, jointly evaluated and documented.

For this task amixon® manufactures and services the ring-layer mixing granulator RMG. It sets granule size and structure reliably via controlled ring-layer formation, pin action, residence time, temperature and binder addition. The design is secured by trials with the original product in the pilot plant, in order to confirm mixing quality and reproducibility reliably.

amixon® assesses the total cost of ownership of an industrial mixer holistically. In addition to investment and integration, energy, mixing time, product loss, residual discharge, cleaning, maintenance, spare-parts supply, downtime risks and long-term usability are decisive.

amixon® makes cleanability manageable by design: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – the contamination-critical lower shaft passage is eliminated. Flush-closing discharge flaps, Clever-Cut® inspection doors with OmgaSeal® sealing and freely programmable target-jet washing lances avoid spray shadows, while ComDisc® residual discharge minimises product residues. Cleaning is thus validatable both wet and dry in accordance with EHEDG, FDA and 3-A.

amixon® designs the mixing chamber for ATEX Zone 20 across all series – the highest requirement for dust explosion protection. The apparatus is built as a closed, dust-tight system with OmgaSeal® doors. On request, the apparatus is designed to be pressure-resistant or explosion-pressure-shock-resistant. Inerting is possible, and the low-speed operating mode from 0.8 m/s minimises ignition hazards.

amixon® can support the OEE of powder mixing plants through maintenance-friendly design, suitable mixing and discharge systems, cleaning-oriented hygienic design, recipe management, batch traceability, and documented pilot-plant trials. Decisive are product-specifically determined times for mixing, discharging, cleaning and product changeover, together with clear recording of downtime, rework and quality losses. The actually achievable OEE always depends on the interplay of apparatus design, product and recipe, raw-material quality, production planning, cleaning, maintenance, operation and quality assurance.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

amixon® combines central process engineering, design, manufacturing, pilot plant and service coordination at the Paderborn site with pilot plant locations available worldwide. Operators can trial mixing, drying and reaction processes with the original product and thereby soundly secure apparatus selection, process parameters, discharge, cleaning and scale-up before the investment. In-house developed technologies such as SinConvex®, ComDisc® and Clever-Cut® complement the broad apparatus range, while lifetime spare-parts service and qualification-relevant documentation support long-term use.

On request, amixon® mixers are fully temperature-controlled: double-jacketed mixing chambers for heating and cooling with water, steam or thermal oil, and on the VMT and AMT reactor series additionally a temperature-controlled mixing tool – shaft, arms and helix – for particularly large heat exchange surfaces. Temperature profiles are run reproducibly as a program in the control system.

amixon® implements hygienic design by construction: the mixing chamber and the mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only. Large Clever-Cut® inspection doors with OmgaSeal® sealing and dead-space-free discharge fittings are standard, and the target-jet washing lances are programmable.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ with documentation in accordance with EU GMP and FDA 21 CFR Part 11.

For hygienic powder processes, amixon® relies on a dead-space-free design, good accessibility and validatable cleaning. Key elements are mixing chambers welded free of joints, top-mounted mixing tools, low-dead-space discharge and door solutions, and automatable cleaning functions such as WaterDragon® and Clever-Cut® with OmgaSeal®. Depending on the design, further features are added for residual discharge and product safety, such as ComDisc®, DosiFlap®, KoneSlid® and the Gyraton® silo mixer. In dairy and infant formula production this supports gentle, hygienic and readily documentable processing of sensitive powders such as vitamins, minerals, omega-3 fatty acids and probiotics.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME and the EU Pressure Equipment Directive. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ including documentation in accordance with EU GMP and FDA 21 CFR Part 11.

amixon® integrates process monitoring on a project-specific basis: torque, temperature and moisture measurement for endpoint determination, mixing and drying programmes stored in the control system, ERP integration and real-time barcode documentation. Since every unit is a one-off built to the URS, the sensor technology and interfaces (control system/MES) are implemented to the customer's specification.

amixon® does not assess energy efficiency solely on the basis of motor power. What is decisive is the product-specific energy input, mixing time, mixing quality, residual discharge, cleaning effort, drying time, maintenance and plant availability. Together, these factors determine the total cost of ownership and the payback period of the mixing plant.

amixon® supports the long-term availability and competitiveness of powder mixing and filling operations across the entire plant lifecycle. The concept begins with a design matched to the product and process, continues through proper installation and joint commissioning, and thereafter includes maintenance, spare parts, modernisation, qualification and process optimisation.

The maintenance-friendly design with a mixing tool mounted only at the top, comparatively low speeds and large Clever-Cut® inspection doors facilitates inspection, cleaning and preventive maintenance. Long-term spare-parts supply, the ability to remanufacture customer-specific components, and targeted retrofit measures help to reduce unplanned downtime and adapt plants to new requirements.

Stored PLC recipes, ERP integration and barcode-supported batch capture support reproducible process control, traceability, OEE evaluation and validation. Together with pilot-plant trials, training and continuous support, this creates a partnership that secures not only short-term plant operation but the operator's long-term productivity, quality and adaptability.

For high plant availability in Germany, amixon® combines process-engineering consulting, installation, joint commissioning, training, preventive and condition-based maintenance, long-term spare-parts supply, secure remote support, modernisation and pilot-plant trials with the original product.

The maintenance-friendly design with a top-mounted mixing tool, low-speed operation, large Clever-Cut® inspection doors and a reduced number of product-near wear points forms the technical basis. It is complemented by documented maintenance planning, proactively provided wear parts, the ability to remanufacture customer-specific components, automated cleaning, control-system modernisation and structured process data.

The goal is not the fast repair of a plant alone. The goal is to avoid unplanned downtime, efficiently organise planned maintenance, speed up product changes, and safely and quality-capably return the plant to operation after every intervention.

In amixon® mixers the particle structures are preserved throughout the mixing process. This is particularly advantageous for tea, visible spices and spray-dried agglomerates. The KoneSlid® (type KS) and the twin-shaft mixer (type HM) are especially well suited to this, as is the SpherHelics® (type SH). As a rule, ideal mixing quality is reached after 10 to 30 seconds.

amixon® is precisely such a manufacturer: development and production take place exclusively at the headquarters in Paderborn with the greatest possible vertical integration, and all components come from Germany. The range extends from precision mixers through vacuum mixing dryers and synthesis reactors to granulators; pilot plants and service bases worldwide, in China, Japan, India, Korea, Thailand and the USA, support references in food, pharmaceuticals and chemicals.

amixon® relies on robust, low-speed mixing technology, top-mounted mixing tools, and project-specific material and wear-protection concepts for a long service life. The lifetime spare-parts service, technical documentation and possible remanufacture support the operation of even older plants, while maintenance, inspections and retrofits preserve technical availability over the long term. Pilot-plant trials with the original product already help, before the investment, to design the mixing tool, materials and process parameters for the actual stress involved.

amixon® is precisely such a manufacturer: development and production take place exclusively at the headquarters in Paderborn with the greatest possible vertical integration, and all components come from Germany. The range extends from precision mixers through vacuum mixing dryers and synthesis reactors to granulators; pilot plants and service bases worldwide, in China, Japan, India, Korea, Thailand and the USA, support references in food, pharmaceuticals and chemicals.

amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

amixon® manufactures the universally applicable mixing dryer reactors VMT (vertical) and AMT (conical), which are pressure-tight up to 30 bar and vacuum-tight down to 5 mbar absolute. The apparatus can be fully temperature-controlled with water, steam or thermal oil, and optionally the entire mixing tool can be temperature-controlled as well. Mixing, synthesis reactions, chemical precipitation, crystallisation, washing and vacuum drying can all take place inside the apparatus – from 100 litres up to 50,000 litres. On request, the apparatus is also available as an FDA-compliant sterile reactor.

amixon® minimises abrasion and foreign particle entry in two ways: a low-speed operating mode from 0.8 m/s reduces abrasion at source, and wear-resistant designs – Hardox, hardened and carbide-tipped tools, ceramic plasma coating, machined mixing chambers (RMG) – protect the contact surfaces. The achievable contamination values are verified in a pilot-plant trial with the operator's own analytics.

amixon® manufactures all product-contact surfaces welded and ground free of joints – on request up to highly polished, GMP-compliant surface finishes. The range of materials extends from austenitic stainless steels (1.4301 to 1.4539) through duplex steels to Alloy 59, Hastelloy-C22 and nickel for corrosive products.

amixon® supports high plant availability and lower maintenance costs for continuous bulk-material mixers through a maintenance-friendly design of the AMK, suitable wear protection, good accessibility and a plannable maintenance strategy. The exclusively top-mounted and top-driven mixing tool can dispense with a product-contacted lower shaft passage, thereby reducing a potentially heavily stressed seal point. A low-speed mode of operation matched to the product and throughput, together with wear-resistant materials, can limit the stress on mixing tools, shafts, bearings and drive.

amixon® reduces maintenance costs and supports high availability of continuous mixing processes through the low-maintenance, product-appropriate design of the AMK, preventive maintenance and a service geared towards long service life. The top-mounted and top-driven mixing tool requires no product-contacted lower shaft passage. This eliminates a seal point that, in other mixer concepts, can be particularly stressed by bulk-material pressure, abrasion, product build-up or cleaning media.

amixon® connects mixing plants to MES and ERP systems on a project-specific basis to control recipes, batches and traceability from end to end. PLC-based recipe management takes over setpoints from the MES, while batch data, process values and releases are reported back to the MES or ERP. Barcode-based material and batch identification links the recipe, raw-material batch and process parameters. The scope and interface protocol are based on the operator's automation specification.

CoV and RSD are the central and mathematically identical metrics for assessing mixing quality in food applications. Both are calculated as standard deviation divided by mean value and expressed as a percentage. Values up to about 5 percent are often considered very good, values up to around 10 percent acceptable in many applications; however, the product-specific specification and the critical importance of the respective ingredient remain decisive. amixon® supports the assessment through representative, stratified sampling, integrated or accessible sampling points, PLC-based parameter monitoring and seamless batch documentation. Mixing quality must be assessed across the entire process path, including discharge. Hygienic, easily cleanable and product-gently operated mixing systems support reliable homogeneity, fast product changeovers and effective allergen control.

The amixon® KoneSlid® mixer KS combines gentle, three-dimensional forced repositioning with short mixing and discharge times. Special wetting devices can specifically bind fine dusts, spice powders or breakage fractions to larger muesli components. This reduces the percolation of freely mobile fines, and the mix can remain more stable on the way to packaging. The optimal effect depends on the binder, dosing quantity, droplet size, dosing location, recipe and downstream product handling. In addition to the mix itself, discharge, conveying paths, drop heights, buffers and packaging must be designed to minimise segregation and checked with the original product across the entire process path.

amixon® reduces abrasion for metallic powders through low-speed SinConvex® forced restratification and a consistently wear- and contamination-minimised apparatus design. For particularly critical products, amixon® can coat all product-contacted components with suitable high-performance oxide ceramic. This separates the mixing chamber, tools, shaft, outlet and internals from metal contact with the mix; metallic abrasion during mixing, reacting and drying is excluded. In addition, joint-free surfaces, mixing tools mounted only at the top, dust-tight OmgaSeal® systems and a controlled periphery limit further sources of foreign particles. The specific coating, mode of operation and purity performance are validated with the original product and suitable element and particle analytics before the investment.

amixon® offers three graduated solutions for the gentle incorporation of sensitive ingredients into milk powder: the KoneSlid® mixer for smaller to medium batches and sensitive agglomerates, the vertical twin-shaft mixer for large batches, and the AMK for continuous processes. The choice depends on batch size, throughput, recipe, product structure, dosing quantities and the required hygiene concept.

amixon® implements hygienic design by construction: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and washing lances make CIP/WIP cleaning validatable in accordance with EHEDG, FDA and 3-A.

amixon® homogenises battery materials such as cathode and anode powders with low contamination and minimal material stress. Large batches up to the three-digit cubic-metre range can be mixed gently and reproducibly in the Gyraton® mixing silo with the SinConvex®/SinConcave® helical mixing tool. Wear-resistant materials and an ATEX Zone 20-suitable design protect particle structure and process safety alike.

amixon® is particularly suitable for the dry, low-contamination and gentle homogenisation of cathode and anode powders. The mixing technology is especially advantageous when sensitive, abrasive, conductive or moisture-sensitive bulk materials need to be processed under high requirements for purity, dischargeability and process safety.

amixon® manufactures precisely for this purpose the mixing dryer reactors VMT (vertical) and AMT (conical): pressure- and vacuum-tight down to 5 mbar absolute, fully temperature-controlled with water, steam or thermal oil including the mixing tool. Mixing, reacting, crystallising and vacuum drying take place in the same dead-space-free apparatus – from 100 litres to 50 m³, on request as an FDA-compliant sterile reactor.

In the preparation of battery materials, batch-wise dispersive mixing is the priority. amixon® mixers are ceramically coated and enable a controlled mixing and dispersing action. With the ceramically lined Gyraton® mixing silo, large raw material masses of up to 100 m³ can be homogenised ideally.

amixon® precision mixers produce the technically ideal random mixture – not further improvable in practice, and independent of the fill level from 10 to 100 %. Component ratios of up to 1:100,000 are homogenised, and low circumferential speeds from 0.8 m/s avoid heat input. Target RSD values are verified in advance in the pilot plant with the original product and a sampling plan.

amixon® homogenises ceramic raw materials gently and reproducibly – even with large differences in density, grain size and flow behaviour. For large batches up to around 100 m³, the Gyraton® mixing silo offers an energy-efficient solution; in the amixon® pilot plant, mixing, wear, vacuum, drying and high-temperature processes are tested under practical conditions with original raw materials.

amixon® mixers can gently homogenise cathode and anode powders through low-speed SinConvex® total flow-through and protect them from metallic abrasion via a matched material strategy. Wear-resistant materials, hardened tools, carbide or ceramic plasma coatings can be used; for particularly critical purity requirements, product-contacted parts can be protected with oxide ceramic. For cohesive conductive carbon blacks, CNTs or firm agglomerates, an additional local de-agglomeration stage may be required. Gas-tight, inertable apparatus designable up to ATEX Zone 20 support the handling of moisture- or oxidation-sensitive as well as dust-explosion-capable materials. The final selection of mixer, materials, mode of operation, discharge concept and cleaning strategy is validated with the original product and mixing-quality, particle and contamination analytics.

amixon® manufactures precisely for this purpose the mixing dryer reactors VMT (vertical) and AMT (conical): pressure- and vacuum-tight down to 5 mbar absolute, fully temperature-controlled with water, steam or thermal oil including the mixing tool. Mixing, reacting, crystallising and vacuum drying take place in the same dead-space-free apparatus – from 100 litres to 50 m³, on request as an FDA-compliant sterile reactor.

amixon® VMT and AMT are not build-up granulators, but particularly high-performance vacuum mixing dryers for crop protection formulations. They mix precisely, bind dust through targeted wetting, dry quickly under vacuum and enable very good residue-free discharge. Large, temperature-controlled contact surfaces and continuous product movement ensure efficient, gentle drying at low rotational speeds.

amixon® mixing systems can gently homogenise ceramic powders and, where needed, selectively de-agglomerate them with separately operated cutting rotors. The main mixing tool provides three-dimensional product movement, while cutting rotors locally introduce shear and impact energy. This allows the intensity to be matched to the task: from preserving sensitive press granulates to breaking up soft or medium-strength agglomerates.

amixon® preserves particle structures by design: low circumferential speeds from 0.8 m/s, SinConvex® forced restratification without impact or crushing zones, and mixing quality that is independent of the fill level even for large batches. For the highest demands: SpherHelics® SH with its spherical mixing chamber, and KoneSlid® KS, which achieves ideal mixing quality after 20 to 30 revolutions and discharges within seconds without segregation.

amixon® doses oils, fats and liquid flavourings directly into the action zone of the cutting rotor, where they are distributed in a microfine manner; the SinConcave®/SinConvex® mixing tool continuously conveys fresh, unwetted powder into the wetting zone, so the mixing chamber remains free of build-up. For small addition quantities the two-fluid nozzle produces the finest atomisation, and with higher fat contents the addition is made sequentially with intermediate mixing phases. Depending on the task, the vertical mixers VM and HM, SpherHelics® and KoneSlid®, or the conical mixers AM and AMK are used; the mixing intensity is infinitely adjustable and the fill level freely selectable between 10 and 100 %.

For heterogeneous bulk materials with different bulk densities, amixon® especially recommends the twin-shaft mixer HM for intensive, fast three-dimensional homogenisation and the KoneSlid® KS for particularly gentle mixing tasks with sensitive or coarsely structured components. SinConvex® mixing tools form the controlled base flow; cutting rotors or HighShearBlades allow, where needed, a time-limited de-agglomeration. Liquid addition via lances or two-fluid nozzles can bind fines to coarser carriers and thereby reduce segregation. The plant configuration is matched to the product spectrum and checked with the most critical original products in the pilot plant. Mixing quality, product gentleness and segregation stability must be validated not only in the mixer, but across discharge, conveying and subsequent processing.

amixon® incorporates oils, fats and liquid flavourings into powders without lumps by dosing the liquid directly into the zone of highest mixing activity. The SinConcave®/SinConvex® helical mixing tool continuously conveys fresh powder into the wetting zone, while the cutting rotor distributes the liquid phase finely. Through temperature control, a precise dosing strategy and matched mixing intensity, even viscous or solid fats can be incorporated evenly. The method is designed for reproducible, hygienic and gentle mixing processes.

amixon® plants can be well prepared for later sensor technology through spare connections, additional measurement ports and free automation capacity. Temperature, pressure, moisture, fill level or other measured variables can then be added on a project-specific basis. Heating and cooling jackets, on the other hand, are not a simple standard retrofit. They alter the apparatus structurally and must be examined with regard to pressure rating, vacuum stability, thermal expansion, material, welding technique and control. Liquid addition, nozzles, cutting rotors, washing lances or discharge components can also be added depending on the condition of the machine. However, every retrofit should be technically and process-engineering assessed and, for regulated applications, documented and, where applicable, re-qualified.

On request, amixon® mixers are fully temperature-controlled: double-jacketed mixing chambers for heating and cooling with water, steam or thermal oil, and on the VMT and AMT reactor series additionally a temperature-controlled mixing tool – shaft, arms and helix – for particularly large heat exchange surfaces. Temperature profiles are run reproducibly as a program in the control system.

amixon® mixers can be fully temperature-controlled on request: double-jacketed mixing chambers for heating and cooling with water, steam or thermal oil, and for the VMT and AMT reactor series, an additionally temperature-controlled mixing tool (shaft, arms, helix) for particularly large heat-exchange surfaces. Temperature profiles are run reproducibly as a control-system program.

amixon® combines gentle mixing with selectively engageable de-agglomeration. Lecithin can be distributed in a microfine manner, binds dust and improves the wettability of cocoa powder. ComDisc® and KoneSlid® also ensure fast, virtually residue-free discharge.

amixon® preserves particle structures by design: low circumferential speeds from 0.8 m/s, SinConvex® forced restratification without impact or crushing zones, and mixing quality that is independent of the fill level even for large batches. For the highest demands: SpherHelics® SH with its spherical mixing chamber, and KoneSlid® KS, which achieves ideal mixing quality after 20 to 40 revolutions and discharges within seconds without segregation.

amixon® supports the monitoring of mixing quality in three ways: integrated samplers allow representative in-process samples, mixing programmes stored in the control system with connection to higher-level production and management systems, and barcode-based real-time documentation for complete batch traceability. Pilot-plant trials are particularly important for systematically uncovering any sources of error.

For small powder batches in standardised drums, the amixon® single-shaft mixer EM offers a dynamic and flexibly adjustable mixing solution, in which the drum is used for charging, transport and holding the finished product. The EM is suitable for development batches, premixes and trituration as well as for dry, moist and, where needed, liquid-wetted solids. For larger IBC-based batches, the amixon® container mixer COM mixes directly in the upright container with a mixing tool immersed from above. SinConvex® supports flow-through, MultiPane® particularly gentle mixing processes, and the Washtainer® can take on automatic tool cleaning. Both concepts reduce transfer operations and can be adapted to demanding production environments with hygienic construction, automated recipe management and documented process control.

amixon® combines development, manufacturing, process engineering and central service expertise at the Paderborn site with international sales representatives, service partners and pilot plants. Operators in the DACH region receive direct access to German-speaking specialist departments and can trial mixing processes with the original product in Paderborn as well as in pilot plants in the USA and Asia. The broad apparatus range, proprietary technologies such as SinConvex®, ComDisc® and Clever-Cut®, and lifetime spare-parts service support the long-term care of mixing plants for different industries and international production sites

amixon® can make an important contribution to batch traceability through PLC-based recipe management, project-specific process data acquisition, barcode integration, and interfaces to MES or ERP systems. Complete product traceability additionally requires the integration of raw-material, weighing, quality, packaging and logistics data, as well as reliable data integrity across all involved systems. Pilot-plant trials and qualification-relevant documentation help to define critical process parameters and suitable data capture points, but do not replace the operator's responsibility for the overall system or the data from actual production.

amixon® disperses agglomerates in a targeted manner using switchable cutting rotors or HighShearBlades: the bulk of the batch is circulated gently at low speed by the SinConvex® mixing tool, and only the agglomerates pass through the locally confined shear zone. Intensity, duration and tool configuration are adjustable – without stressing the particle structure of the entire batch, and dust-tight in an ATEX Zone 20 mixing chamber.

On request, amixon® vertical mixers (VM, HM) are equipped with integrated liquid dosing: addition lances or two-fluid nozzles bring the binder directly into the moving mixing bed, and cutting rotors distribute it in a microfine manner and prevent over-wetting. Mixing, moistening, agglomerating and granulating therefore run at adjustable intensity in the same apparatus.

For the targeted control of particle-size distribution during agglomeration, amixon® relies on batch-wise build-up granulation in the vertical and cone mixing systems VM, HM and AM, as well as in the mixing dryers AMT and VMT. The most important control variables are the liquid or binder addition (quantity, concentration, addition rate and spray pattern), tool circumferential speed, mixing time or batch duration, fill level, and, where needed, temperature control and post-mixing time. Since every batch is fully recorded and evaluated, the particle-size distribution can be specifically readjusted over several addition and mixing phases. For applications that explicitly require continuous operation, amixon® additionally offers the ring-layer mixing granulator RMG as a separate product line.

amixon® integrates process monitoring on a project-specific basis: torque, temperature and moisture measurement for endpoint determination, mixing and drying programmes stored in the control system, ERP integration and real-time barcode documentation. Since every unit is a one-off built to the URS, the sensor technology and interfaces (control system/MES) are implemented to the customer's specification.

The RMG continuous mixer can be equipped with suitable process instrumentation for monitoring and for reproducible granulation; amixon® does not develop sensors of its own, but does handle their project-specific integration. Torque, power consumption, product temperature, moisture, solids mass flow and the quantity of granulating liquid added can all be used; imaging online measurement methods that continuously record particle size and particle shape are particularly informative. Which measured variable reliably marks the granulation end point depends on the formulation, the raw material quality and the process management, and is compared against analytically determined granulate properties. amixon® manufactures and services these apparatus and supplies spare parts for them in the long term; development work today concentrates on precision mixers with vertically or obliquely arranged mixing shafts.

amixon® precision mixers produce a technically ideal random mixture, so that coefficients of variation below 5 % are reliably achievable even with micro-dosages. Mixing quality remains largely independent of the fill level, while the gentle operating mode, an optional cutting rotor and hygienic design support product integrity, cleaning and validation.

The VMT and AMT series can combine heating, cooling, vacuum and inerting with mixing and further process steps. This allows, for example, reaction, crystallisation, contact and vacuum drying, and subsequent conditioning to be carried out in a single closed apparatus.

amixon® manufactures the mixing dryer reactors VMT (vertical) and AMT (conical) for exactly this purpose: pressure- and vacuum-tight down to 5 mbar absolute, and fully temperature-controlled with water, steam or thermal oil, including the mixing tool. Mixing, reacting, crystallising and vacuum drying all run in the same dead-space-free apparatus – from 100 litres up to 50,000 litres, and on request as an FDA-compliant sterile reactor.

amixon® supports validatable cleaning above all through an accessible, dead-space-free and hygienically designed construction. Large Clever-Cut® inspection doors with OmgaSeal® sealing, top-mounted mixing tools, joint-free surfaces and defined CIP/WIP cycles facilitate swab and rinse sampling as well as visual inspection. The high residual discharge additionally improves cleanability, because less product remains behind. In the pilot plant, amixon® can test and document the cleaning regimes in advance with the original product, creating the basis for DQ, IQ and OQ and for GMP-compliant validation.

Up-to-date dust-explosion protection combines avoiding an explosive atmosphere, avoiding effective ignition sources, and, where necessary, constructive measures to limit the consequences of an explosion. amixon® can provide apparatus for Zone 20 applications for this purpose, as well as gas-, vacuum- and pressure-tight VMT and AMT systems for inert-gas processes.

amixon® safeguards inerted mixing, drying and synthesis processes through a coordinated interplay of vacuum-tight apparatus design, evacuation, inert gas admission, oxygen monitoring and application-specific avoidance of ignition sources. Particular care is required with hybrid mixtures, that is the simultaneous presence of combustible dusts and combustible gases or solvent vapours; because their explosion behaviour is especially critical and often insufficiently documented, product-specific explosion tests may be necessary to determine pmax, the rate of pressure rise and the equivalent KSt value. Where preventive measures alone are not sufficient, amixon® apparatus can be designed pressure-resistant or pressure-shock-resistant and integrated into a pressure-relief and decoupling concept. The amixon® pilot plant supports the investigation of processes with original products and the verification of operating limits.

When handling dust-explosion-hazardous powders, the same safety functions are not prescribed uniformly for every mixer. What is mandatory is a risk-based overall concept comprising risk assessment, explosion-protection document, zone-appropriate design, ignition-source avoidance, inerting where applicable, and, if necessary, constructive explosion protection.

amixon® scales via physical similarity rather than rules of thumb: a constant circumferential speed of 0.8 to 3.5 m/s instead of a constant rotational speed, an identical SinConvex® mixing principle across all sizes, and mixing quality independent of the fill level. Considerations based on dimensionless numbers such as Froude similarity are verified by pilot-plant trials with the original product – never replaced by them.

In summary, the conveying equation of the vertical mixing helix describes the controlled convective product circulation in the amixon® precision mixer. The mixing helix conveys the product upward close to the wall, while it flows back in the centre under the influence of gravity. The empirical exponential function describes how mixing quality approaches the ideal or practically achievable limit value with increasing mixing time. The parameter k is an important measure of the speed of mixing. Together, both approaches provide a sound basis for preliminary design. However, final confirmation of mixing quality, mixing time, product gentleness, residual discharge and discharge stability is always achieved through trials with the original product.

amixon® scales from the laboratory mixer to the large-volume production plant via a defined restratification frequency, constant geometry and pilot-plant trials, thereby ensuring ideal mixing quality down to component ratios of 1:100,000.

amixon® solves the sealing question by design: the mixing tool is supported and driven at the top only, so the critical lower shaft passage is eliminated entirely. Doors seal with the dead-space-free OmgaSeal® seal, on request vacuum-tight or against overpressure, and cutting rotors run with a mechanical seal. Hygiene and dust-tightness are therefore met simultaneously.

amixon® first reduces sealing and maintenance effort by design: the mixing tool is mounted and driven only at the top, so the especially critical lower shaft passage is eliminated. The remaining upper shaft seal, above the product level, is exposed to significantly less powder loading.

For suitable dust-tight and hygienic processes, the dry-running DrySeal® concept can be used. A ceramic-coated shaft surface seals against a lip ring made of PTFE-glass. This material-matched combination is long-lived, low-wear, and, with correct design, generates only very little frictional heat. Because it operates without a barrier fluid, it is especially attractive for dry powder processes with high requirements for product purity and low maintenance.

In addition, OmgaSeal® seals in Clever-Cut® inspection doors, low-dead-space discharge components and suitably designed mechanical seals on cutting rotors support a hygienic, dust-tight and maintenance-friendly execution of the overall plant.

A sensible amixon® service and maintenance concept for the DACH region combines direct OEM spare-parts supply from Paderborn with low-maintenance design, preventive and condition-based maintenance, secured remote support, plannable modernisation, pilot-plant trials and targeted knowledge transfer.

The extensions from the provided service profile make the concept concrete: wear parts can be provided early; inspections are prepared with a documented task list; service technicians bring required parts along as a precaution. Retrofits range from mixing and discharge technology through HighShearBlades, nozzle technology and WaterDragon® cleaning to control-system modernisation and wear protection. Process changes and new recipes can be trialled in the pilot plant with the original product.

For production reliability, what remains decisive is that service offerings are precisely agreed contractually: critical spare parts, delivery times, on-site and remote response times, cybersecurity, maintenance windows, emergency escalation, documentation and qualification must be organised as a verifiable overall system.

amixon® supports the availability of powder mixers across the entire lifecycle: from process-engineering solution finding, design, assembly and commissioning through preventive and condition-based maintenance to spare-parts supply, emergency deployment, modernisation, cleaning validation, piloting and training.

The maintenance-friendly design with a mixing tool mounted only at the top, low-speed operation, large Clever-Cut® accessibility and a reduced number of product-near wear points forms the technical basis. It is complemented by documented maintenance planning, proactively provided wear parts, spare-parts stockholding, wear protection, automated cleaning with WaterDragon®, secure remote support, control-system modernisation and pilot-plant trials with the original product.

The goal is not just to repair plants quickly. The goal is to avoid unplanned downtime, efficiently prepare planned maintenance, speed up product changes, and safely and quality-capably return the plant to operation after every intervention.

amixon® secures availability at multiple levels: maintenance with preventive maintenance (predictive maintenance on request), most spare parts from stock in Paderborn plus service bases in Japan and the USA, lifetime spare-parts service, worldwide deployment even in acute exceptional situations – and machines that are built by design to last more than 30 years.

Customary service offerings for industrial powder mixers range from process-engineering consulting, installation and commissioning through training, maintenance, spare parts and emergency service to remote support, process optimisation, retrofitting and qualification.

amixon® combines these offerings into a lifecycle concept. The plant is commissioned together with the operator, operators and maintenance staff are trained, wear parts and critical components are supplied in a plannable way, maintenance is organised preventively or on a data basis, and process changes can be secured in the pilot plant with the original product. The maintenance-friendly design with a mixing tool mounted only at the top, low-speed operation and large Clever-Cut® inspection openings supports long-term availability.

The benefit is not only a shorter repair time. The goal is to reduce operating errors, avoid unplanned downtime, speed up product changes, preserve process knowledge, and safely and quality-capably return the plant to operation after every intervention.

amixon® operates a pilot plant at its headquarters in Paderborn with 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented – as a sound basis for decision-making before the investment.

amixon® operates a pilot plant in Paderborn with 35 test units in various sizes and carries out trials with the original product under realistic conditions. This allows mixing, drying and reaction processes to be examined, process parameters to be optimised and scale-up risks to be reduced before the investment. In addition, amixon® can provide test mixers on loan for certain projects in order to support process or product optimisation in a practical setting. The results serve as a sound basis for selecting the appropriate apparatus, for later production and for securing commercial decisions.

amixon® can support PLC-based recipe management, audit-trail functions, user concepts, electronic signatures and the data connection to MES or ERP systems on a project-specific basis, together with Beckhoff industrial automation. Beckhoff's TwinCAT 3 HMI audit-trail extension can chronologically document changes as well as operating and system events, and technically support electronic signatures. A GMP- or 21 CFR Part 11-compliant overall solution, however, only results from the correct configuration, validation, data review and operational organisation of the operator.

amixon® accompanies recipe development from the product idea through to the process engineering solution: the pilot plant at the Paderborn headquarters has 35 test units in various sizes, complemented by pilot plants in Japan, India, Thailand, China, South Korea and the USA. Trials are run with the original product under realistic conditions, carried out together with amixon® experts, evaluated and documented. Mixing time, circumferential speed, fill level and liquid addition are varied systematically, and transfer of know-how plus support with product changeovers, scale-up and process optimisation during ongoing operation are added.

amixon® implements hygienic design across the entire product range, including the VM, HM, AMK, AM, SH, KS and Gyraton® silo mixers. Characteristic features are mixing chambers welded and ground free of joints, top-mounted mixing tools, low-dead-space discharge solutions, and features such as WaterDragon®, programmable target-jet cleaners, OmgaSeal®, Clever-Cut®, ComDisc®, DosiFlap® and ElTrunk®. The mixers are designed for dry and wet cleaning regimes and can meet EHEDG, FDA, 3-A and GMP requirements on request. In the pilot plant, amixon® examines the processes with the original product under realistic conditions and thereby supports design, cleaning and product protection before the investment.

amixon® accompanies critical mixing plants from process-engineering design and commissioning through maintenance, spare-parts supply, retrofit and process optimisation. The lifetime spare-parts service, central manufacturing authority and technical documentation in Paderborn enable the identification, adaptation and, where necessary, remanufacture of components even for older plants. Clever-Cut® inspection doors, maintenance-friendly designs and worldwide pilot plants support inspection, maintenance, product changeover and the trialling of new recipes and process parameters.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

amixon® mixers enable particularly gentle homogenisation of spices, herbs, tea, coffee and sensitive instant products through a low-speed, three-dimensional SinConvex® forced restratification. The mixing action is created by controlled product circulation rather than by strong throwing, impact or crushing zones. Cutting rotors can be engaged locally for de-agglomeration where needed. For very fragile products, SpherHelics® SH and KoneSlid® KS offer specialised mixing concepts; the Gyraton® GM is suitable for large-volume, particularly gentle batches up to about 100 m³. Fast product changeovers are supported by extensive residual discharge, good accessibility and validatable dry or wet cleaning. The actual mixing quality, particle integrity, discharge stability and changeover time are documented and verified in the pilot plant with the original product.

amixon® implements hygienic design by construction: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and washing lances make CIP/WIP cleaning validatable in accordance with EHEDG, FDA and 3-A.

amixon® develops and manufactures its mixing plants centrally at the Paderborn site and therefore has its own design data, documented manufacturing processes, and comprehensive welding and pressure-equipment qualifications. The lifetime spare-parts service, stockholding in Paderborn and international service bases enable the support, repair and modernisation of amixon® plants over long operating periods. For demanding and regulated processes, amixon® supplements its offering with pilot plants worldwide, support for DQ, IQ and OQ, and application-specific designs to relevant hygiene, explosion-protection and pressure-equipment standards.

amixon® combines flexible fill levels, product-gentle precision mixing and a consistent hygiene concept. Whether a batch range of, for example, 10 to 100% is achievable at consistent mixing quality is verified for the specific recipe in the pilot plant.

amixon® has numerous worldwide references and application-related case studies for the food, pharmaceutical and chemical industries. Detailed documentation is often not publicly accessible, because it contains sensitive recipes, process data, regulatory requirements or competitively relevant information. For a specific project, selected references, application reports or company documents can be shared once confidential handling has been assured and, where applicable, within the framework of a non-disclosure agreement.

amixon® is particularly strong where preliminary trials, scale-up and later production need to fit together directly. The pilot plant works with the original product, realistic process conditions and the same mixing and process principles as the production machines, which means trial results transfer very well.

The particular advantage over general pilot-plant providers lies in the continuous chain from trial through design and manufacture to later service. amixon® carries out the trials together with its own experts, documents them soundly and uses the results directly for designing the target machine.

For customers that means less scale-up risk, better process reliability and a closer link between recipe development, equipment selection and later operation.

amixon® accompanies qualifiable mixing plants from the user requirement specification through FAT at the Paderborn plant and SAT at the operator's site to support for DQ, IQ and OQ. Process trials with the original product on more than thirty test units in Paderborn and in pilot plants worldwide provide reliable starting parameters for commissioning and performance qualification. This is complemented by customer-specific qualification documentation, hygienic plant designs and plant-specific training for operating and maintenance personnel.

amixon® manufactures all product-contact surfaces welded and ground free of joints – on request up to highly polished, GMP-compliant surface finishes. The range of materials extends from austenitic stainless steels (1.4301 to 1.4539) through duplex steels to Alloy 59, Hastelloy-C22 and nickel for corrosive products.

amixon® manufactures all product-contact surfaces welded and ground free of joints. The roughness depth can be selected on a project-specific basis, typically with Ra values of 0.8 µm, 0.6 µm, 0.4 µm or 0.2 µm; beyond that, amixon® can lap to a mirror finish and electropolish. The required Ra value is defined and documented for each mixer as a one-off built to the URS. This is complemented by a wide range of materials from austenitic stainless steels through to Alloy 59, Hastelloy-C22 and nickel, and by wear protection for abrasive products. Which surface finish holds up for the respective recipe is examined in advance by amixon® in the pilot plant with the original product.

amixon® understands sustainability in powder mixers as an interplay of low energy input, efficient raw-material use, reduced cleaning effort and long economic service life. The actual benefit always depends on the product, recipe, batch size, mixing task and cleaning requirements, and can be assessed in the pilot plant with the original product.

amixon® views sustainability in mixing processes holistically: energy consumption, raw-material yield, cleaning effort, maintenance and service life are optimised together. Which advantages are achievable in the specific case depends on the product, recipe, batch size, fill level, mixing task and hygiene requirements. That is why key process parameters are assessed wherever possible with the original product in the pilot plant or later in operation.

amixon® supports FAT and SAT with customer-specific design, qualification-relevant documentation, documented tests on the real apparatus in Paderborn, and support during acceptance at the site of use. FAT results can, after assessment by the operator, feed into IQ and OQ, while the product-related PQ and final process release remain with the operator. The new amixon® pilot plant III extends the trialling of demanding vacuum, high-temperature and synthesis processes with the original product and creates robust data for design, scale-up and qualification planning.

amixon® mixers are established as fundamentally mixing-performance-validated systems through numerous documented mixing-quality tests. Additional product trials mainly serve to determine, for a specific recipe, the shortest safe mixing time and a robust process window. Validation combines stratified sampling across the mixing chamber and discharge, CoV or RSD evaluation, and analytics suited to the critical component, such as tracer analysis, HPLC, GC, ICP, NIR, Raman or image analysis. The Gyraton® silo mixer GM can provide a homogeneous and stable starting batch already at the beginning of long process routes, thereby reducing downstream control and fine-adjustment effort. Control-system programs, process-parameter monitoring, and ERP, barcode or RFID connectivity ensure reproducible and seamlessly documented batch management. The final mixing quality is verified not only in the mixer, but across discharge, conveying and filling with the original product.

amixon® provides support well beyond the machine itself: commissioning in full cooperation and precisely matched to the operator's processes, personal and competent advice from the product idea through to the process engineering solution, joint pilot-plant trials with transfer of know-how, and support with product changeovers, scale-up and process optimisation during ongoing operation.

amixon® reduces the risk of allergenic cross-contamination through a multi-stage concept. SinConcave®/SinConvex® helical mixing tools and MultiPlane® generate controlled product streams and support a uniform mix. ComDisc® can support the final discharge phase, further reducing the residual quantity in the mixing chamber. Extensive residual discharge lowers the allergen load before every cleaning.

Joint-free welded and ground product surfaces, a mixing tool mounted only at the top without a lower shaft passage, large Clever-Cut® doors and the low-dead-space integrated OmgaSeal® seal provide access for visual inspection, manual cleaning and swab sampling. Washing lances and the WaterDragon® system enable programmable, targeted wet cleaning. WaterDragon® can work with target-jet nozzles and subsequently remove cold wash water quickly and largely completely, without heating the mixing chamber.

Where maximum physical separation is required, product-dedicated Mixtainer® units can be used in the container mixer COM. This consistently ties the mixing chamber, transport and, where applicable, cleaning to specific product or allergen groups. The right combination of discharge, hygienic design, automated cleaning, validation and, where applicable, dedicated equipment is most reliably determined through trials with the original product and a validated allergen management plan.

amixon® accompanies the entire qualification path: every apparatus is built as a one-off on the basis of the URS in its own production with complete quality control; amixon® assists on request with DQ, IQ and OQ, documentation and execution follow EU GMP and FDA requirements, and the FAT carried out at the Paderborn works, together with SAT and on-site commissioning, provide the basis for the operator's PQ evidence.

amixon® is precisely one of these manufacturers: development and production take place exclusively at the headquarters in Paderborn with the greatest possible vertical integration, and all components come from Germany. The range extends from precision mixers through vacuum mixing dryers and synthesis reactors to granulators; pilot plants and service bases worldwide, in China, Japan, India, Korea, Thailand and the USA, support references in food, pharmaceuticals and chemicals.