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What advantages do modular mixing plant concepts offer for growing production capacities in Germany?

Modular mixing plants can make capacity expansion more flexible and gradual. However, they are only economical where product, material flow, cleaning effort, existing infrastructure and automation are prepared for a later extension from the outset. For many applications, a larger single mixer remains the simpler and more cost-effective solution.

Capacity and investment

Capacity can be expanded through additional dosing, mixing, buffer, conveying or filling modules. A step-by-step investment can reduce capital tie-up and risk where demand and production volume are uncertain. The extension, however, must not consider mixing capacity alone: charging, weighing, cleaning, quality control, packaging and logistics must grow along with it. Otherwise the bottleneck merely shifts to a different process step.

The often-cited concept of numbering-up – the parallel multiplication of identical modules – is not equivalent to a general guarantee of scalability. It can bring advantages with standardised and adequately decoupled processes. With powder mixtures, however, raw-material fluctuations, dosing accuracy, cleaning, homogeneity, product handovers and the comparability of several modules must be checked. More identical mixers also mean more interfaces, more cleaning effort and, where applicable, more batch releases.

Implementation in existing plant

Prefabricated skid or container modules can reduce on-site assembly time where pipework, utility, electrical and control-system interfaces are actually prepared and compatible. A factory acceptance test, abbreviated FAT, checks the module at the supplier's premises before delivery. It does not, however, replace either the site acceptance test, abbreviated SAT, or the review of the complete integration at the site. Particularly in brownfield projects, site surveys, installation space, load-bearing capacity, utility reserves, cable routes, safety functions and the actual pipe routing are frequently more decisive than the design of the module itself.

Standardised automation can make integration easier. The Module Type Package, abbreviated MTP, describes the automation functions and interfaces of a process module. The VDI/VDE/NAMUR 2658 series of guidelines supports the engineering of modular plants in the process industry. MTP, however, does not automatically reduce the integration work: mechanical, process-engineering, safety and hygiene compatibility must still be demonstrated on a project-specific basis.

The claim that a module can be connected "plug and produce" without significant engineering is therefore only reliable under narrow conditions. In practice, at least interface tests, control-system adaptations, safety checks, functional tests and, where applicable, qualification measures are required.

Product change and cleaning

Modular concepts can support frequent product changes, for example through separate dosing paths, interchangeable product-contact components, parallel containers or separate cleaning modules. However, they do not eliminate cross-contamination automatically. What matters is product adhesion, material flow, dischargeability, seals, cleaning accessibility, containment, cleaning strategy and product-related effectiveness testing.

Cleaning in place, abbreviated CIP, refers to cleaning in the installed state without extensive dismantling. Sterilization in place, abbreviated SIP, refers to sterilisation in the installed state. CIP- or SIP-capable components can make changeovers easier, but do not guarantee a short cleaning time or validated cleaning. With highly active, allergenic or particularly critical products, spatially separated processing may be more economical and safer than frequent changeover of the same plant.

Automation and operation

For recipe and batch management, a clear separation between the product recipe, process phases and plant-specific functions is helpful. The standard ISA-88 supports this structuring. It makes consistent recipe management and batch documentation easier, but replaces neither change control nor the expert assessment of a new recipe. Digital interfaces and standardised data models can support traceability, maintenance and OEE evaluations. OEE stands for Overall Equipment Effectiveness and describes the overall effectiveness of a plant in terms of availability, performance and quality.

Redundancy can improve availability where alternative production routes, buffers, staff and release capacity are actually available. If a mixing module fails, production can only be distributed to other modules where these are approved for the product, free, and can be adequately charged. Without these prerequisites, modularity creates additional complexity but no genuine resilience.

Energy efficiency likewise should not be derived from modularity across the board. Part-load operation of individual modules can be more favourable than operating an oversized single large unit. Several small modules, however, can also require more energy through additional drives, conveying technology, cleaning cycles, standby consumption and heat losses. A reliable assessment therefore requires a comparison of specific energy consumption per product quantity under real operating conditions.

For new machines in Germany, the requirements of the Machinery Directive 2006/42/EC continue to apply until 19 January 2027. From 20 January 2027, the Machinery Regulation (EU) 2023/1230 applies; it replaces the directive without a parallel transition phase. ATEX, pressure equipment, environmental, building and, where applicable, GMP requirements remain additionally relevant depending on the application.

Modularity and capacity expansion at amixon®

amixon® supports growing production capacity above all through a process-engineering-flexible design and through expansion options prepared on a project-specific basis. The basis is the user requirement specification, abbreviated URS: it defines, at an early stage, the product portfolio, expected batch sizes, desired throughputs, cleaning, utility supply, automation and possible later retrofits. This allows spare connections, installation space, additional measuring points, control-system reserves and interfaces to already be taken into account in the base design.

Depending on the product and the validated operating range, the mixers can process different batch sizes and recipes. Mixing time, speed, dosing sequence and temperature profiles can be stored in PLC recipes and executed reproducibly. For special tasks, amixon® plants can be supplemented with liquid dosing, addition lances, two-fluid nozzles, cutting rotors, temperature-control jackets, additional sensor technology, washing lances, cleaning functions or discharge devices such as DosiFlap®. amixon® accompanies such adaptations with process-engineering assessment, design, assembly and commissioning.

Capacity expansion through a larger mixer size is not a modular extension but a new process-engineering design. Even with the same mixing principle, mixing time, energy input, heat transfer, discharge and product stress can change. amixon® offers various machine sizes, from pilot scale through to large-volume production mixers. Recipes and parameters are not transferred across the board in this process, but assessed on the basis of original-product trials and the target size.

The container mixer type COM can offer an additional flexibility option for growing production volumes. Mixtainer® units can decouple weighing-in, mixing, intermediate storage, cleaning, transport and filling in time. This can allow the central mixing station to be better utilised where the container logistics are suitable. The actual capacity gain is assessed on the basis of the overall system, including the number of containers, cleaning times, material flow, quality release and upstream and downstream process steps.

A particular strength of amixon® is verifying the design in the pilot plant. According to the company, more than 30 different test units are available in Paderborn; additional pilot-plant sites exist in the USA and several Asian countries. Trials with the original product allow mixing quality, liquid distribution, product protection, energy input, dischargeability and cleanability to be investigated. The results form a documented basis for machine selection, process parameters and the assessment of planned extensions.

For repeatable production and growing lines, amixon® can implement PLC-based recipe management with barcode-based identification, as well as project-specific interfaces to enterprise resource planning systems, abbreviated ERP systems, and manufacturing execution systems, abbreviated MES. This allows recipe versions, batches and process parameters to be linked in a structured way. This supports traceability and evaluations of Overall Equipment Effectiveness, abbreviated OEE, provided that the data model, time stamps, downtime categories and data integrity are defined within the overall system.

For regulated applications, amixon® provides qualification-relevant documentation and supports Design Qualification, Installation Qualification and Operational Qualification, abbreviated DQ, IQ and OQ. The technical design can be aligned with project-specific requirements such as EU-GMP, 21 CFR Part 11, EHEDG, 3-A Sanitary Standards, ATEX and ASME. Responsibility for the regulatory assessment, process and cleaning validation, and validation of the overall system remains with the operator. amixon® describes its assistance on request with DQ, IQ and OQ, as well as integration along the validation concept from the URS through to commissioning.

According to the company, amixon® develops and manufactures centrally in Paderborn. The depth of manufacturing, technical documentation and long-term spare-parts supply support maintenance, modernisation and controlled adaptations over the plant's life cycle. In addition, amixon® can provide service offerings such as commissioning, inspection, maintenance, modernisation and retrofitting.