Dairy / Milk Powder / Infant Formula

A low-risk scale-up from 20 litres to 2,000 litres for infant formula is best achieved through pilot-plant trials with the original product, so that mixing quality, product protection and process stability are examined under realistic conditions. The amixon® pilot plant has 35 test mixers of up to 3 m³ available for this, offering the highest possible degree of process proximity and certainty for the later production scale.

amixon® makes cleaning validatable: a dead-space-free, fully accessible design with Clever-Cut® doors for swab and rinse sampling, CIP/WIP via washing lance, and residual discharge of up to 99.997 %. amixon® assists on request with DQ, IQ and OQ, with documentation in accordance with EU GMP and FDA 21 CFR Part 11 – from the URS through to commissioning.

amixon® avoids the most critical sealing point by design, because the mixing tool is supported at the top only and there is no lower shaft passage. Complemented by the dead-space-free OmgaSeal® seal in the Clever-Cut® design, mechanical seals and dismantlable lip seals on rotating passages, and the high dimensional rigidity of the apparatus, the result is hygienic, dust-tight and durable sealing solutions requiring very little maintenance.

amixon® solves this by design with three alternatives: the KoneSlid® mixer (KS) and the vertical single- and twin-shaft mixers (VM and HM). They are welded and ground free of joints, and the mixing tool is supported at the top only, with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and integrated programmable washing lances enable validatable cleaning – wet as well as dry – in accordance with EHEDG, FDA and 3-A.

For hygienic powder processes, amixon® relies on a dead-space-free design, joint-free and readily accessible mixing chambers, and validatable cleaning. This includes Clever-Cut® inspection doors, OmgaSeal® seals, top-mounted mixing tools, and freely programmable target-jet cleaning nozzles and washing lances for reproducible CIP and WIP cycles. ComDisc® and the SinConcave®/SinConvex® mixing helix additionally ensure particularly good residual discharge and a low risk of cross-contamination. In dairy and infant formula production this improves hygiene, cleanability and product protection, and is secured in advance in the pilot plant with the original product.

amixon® implements freedom from dead space and hygienic design through mixing chambers welded and ground free of joints, top-mounted mixing tools without a contamination-critical shaft passage, and flush-closing discharge flaps, Clever-Cut® doors and OmgaSeal® door seals. This is complemented by freely programmable target-jet cleaners, a method for fast and effective drying in the cold state, and ComDisc® residual discharge for maximum discharge and minimal cross-contamination risk.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ with documentation in accordance with EU GMP and FDA 21 CFR Part 11.

amixon® makes cleanability manageable by design: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – the contamination-critical lower shaft passage is eliminated. Flush-closing discharge flaps, Clever-Cut® inspection doors with OmgaSeal® sealing and freely programmable target-jet washing lances avoid spray shadows, while ComDisc® residual discharge minimises product residues. Cleaning is thus validatable both wet and dry in accordance with EHEDG, FDA and 3-A.

amixon® implements hygienic design by construction: the mixing chamber and the mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only. Large Clever-Cut® inspection doors with OmgaSeal® sealing and dead-space-free discharge fittings are standard, and the target-jet washing lances are programmable.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ with documentation in accordance with EU GMP and FDA 21 CFR Part 11.

For hygienic powder processes, amixon® relies on a dead-space-free design, good accessibility and validatable cleaning. Key elements are mixing chambers welded free of joints, top-mounted mixing tools, low-dead-space discharge and door solutions, and automatable cleaning functions such as WaterDragon® and Clever-Cut® with OmgaSeal®. Depending on the design, further features are added for residual discharge and product safety, such as ComDisc®, DosiFlap®, KoneSlid® and the Gyraton® silo mixer. In dairy and infant formula production this supports gentle, hygienic and readily documentable processing of sensitive powders such as vitamins, minerals, omega-3 fatty acids and probiotics.

On request, amixon® meets all relevant standards: EHEDG, FDA hygiene guidelines, 3-A Sanitary Standards, USDA, GMP and ATEX; pressure vessels also to ASME and the EU Pressure Equipment Directive. Every mixer is a one-off built to the URS – amixon® assists on request with DQ, IQ and OQ including documentation in accordance with EU GMP and FDA 21 CFR Part 11.

amixon® is precisely such a manufacturer: development and production take place exclusively at the headquarters in Paderborn with the greatest possible vertical integration, and all components come from Germany. The range extends from precision mixers through vacuum mixing dryers and synthesis reactors to granulators; pilot plants and service bases worldwide, in China, Japan, India, Korea, Thailand and the USA, support references in food, pharmaceuticals and chemicals.

amixon® implements hygienic design by construction: the mixing chamber and mixing tool are welded and ground free of joints, and the mixing tool is supported at the top only – with no lower shaft passage. Clever-Cut® inspection doors with OmgaSeal® sealing, dead-space-free discharge fittings and washing lances make CIP/WIP cleaning validatable in accordance with EHEDG, FDA and 3-A.