Mixer dryer synthesis reactors for active pharmaceutical ingredients (API)

View from above into an amixon® API reactor.

In the production of pharmaceutical ingredients, the efficiency of the mixing technology is of crucial importance, regardless of whether the reactions are biotechnological or chemical. The ultimate goal is complete chemical/biochemical conversion.

Only when the entire reactor content is completely flowed through/mixed can the substances involved in the reaction come into contact with each other, uniformly distributed. Only then can a uniform temperature level be achieved in the reactor. Process temperatures can only be reliably controlled in this way.

Yield, quality and production safety depend directly on the efficiency of the mixing process.

Quality-determining apparatus properties:

It is important that the mixer synthesis reactor works gently.
The mixing tools may only move slowly.
Nevertheless, the mixing quality must always be ideal, regardless of whether it is a liquid, a suspension or a highly viscous mass.
The resulting suspensions, emulsions, crystals, coagulates, aggregates or flakes must not be sheared or damaged.

In order to be able to control the thermokinetic processes reliably, the synthesis reactor/fermenter must have heat exchanger surfaces that are as large as possible. The heat exchanger surfaces must have the same temperatures at all points. Steam, water or thermal oil can be used as heat transfer media. The flow resistance in the heat transfer walls must be kept to a minimum. amixon^® has invested heavily in research and development in this area. amixon^® can offer various solutions depending on the desired batch size. amixon^® can demonstrate the respective efficiencies in its own technical centre.

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